Anterior Pituitary Flashcards

1
Q

List the 6 peptide hormones that are produced in the AP

A
  • PRL
  • GH
  • TSH
  • ACTH
  • FSH
  • LH
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2
Q

Which cell type is the most abundant in the anterior pituitary?

A

Somatotroph

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3
Q

Which hormone of the AP stimulates the adrenal cortex?

A

Adrenocorticotropic hormone (ACTH)

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4
Q

What type of hormones are secreted in response to ACTH?

A

Glucocorticoids

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5
Q

Which glucocorticoid is the stress hormone in animals?

A

Corticosterone

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6
Q

Which glucocorticoid is the stress hormone in Humans?

A

Cortisol

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7
Q

Adrenal glands have _____________ tissue where ACTH acts

A

Steriogenic

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8
Q

What metabolisms are affected with ACTH?

A

Carbohydrate and mineral

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9
Q

What stimulates the release of ACTH from the AP?

A

Corticotropin releasing hormone (CRH)

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10
Q

What inhibits CRH?

A

Glucocorticoids

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11
Q

What secretes CRH?

A

Hypothalamus

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12
Q

CRH is secreted in response to what?

A

Stress

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13
Q

Which part of the adrenal gland produces corticosteroids?

A

Adrenal cortex

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14
Q

Corticosteroids are divided into _________________ and __________________.

A

Mineralocorticoids and glucocorticoids

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15
Q

What is the main mineralocorticoid (causes water retention)?

A

Aldosterone

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16
Q

hydrocortisone = ?

17
Q

Which part of the adrenal gland secretes epinephrine and norepinephrine?

A

Adrenal medulla

18
Q

Which glucocorticoid regulates important Cardiovascular, metabolic, immunologic, and homeostatic functions?

19
Q

Adrenal insufficiency can cause:

A
  • hypotension
  • shock
  • death
20
Q

Is cortisol catabolic or anabolic?

A

Catabolic - breaks protein down

21
Q

What is the effect of cortisol in high levels to the immune system?

A

Depresses the immune response

22
Q

ACTH travels to the adrenal gland to stimulate the secretion of?

A

Glucocorticoids

23
Q

Dehydroepiandrosterone (DHEA) is secreted by the ?

A

Adrenal cortex

24
Q

DHEA is converted into _______ and ___________

A

Testosterone and estrogen

25
Q

The two major portions of the adrenal gland are the ____________ and __________

A

cortex and medulla

26
Q

Which zone of the adrenal cortex produces the mineralocorticoids?

A

Zona glomerulosa

27
Q

The adrenal cortex, apart from corticoid synthesis, can regulate what concentrations?

A

Electrolytes in Extracellular fluids