Anterior Pituitary Flashcards
List the 6 peptide hormones that are produced in the AP
- PRL
- GH
- TSH
- ACTH
- FSH
- LH
Which cell type is the most abundant in the anterior pituitary?
Somatotroph
Which hormone of the AP stimulates the adrenal cortex?
Adrenocorticotropic hormone (ACTH)
What type of hormones are secreted in response to ACTH?
Glucocorticoids
Which glucocorticoid is the stress hormone in animals?
Corticosterone
Which glucocorticoid is the stress hormone in Humans?
Cortisol
Adrenal glands have _____________ tissue where ACTH acts
Steriogenic
What metabolisms are affected with ACTH?
Carbohydrate and mineral
What stimulates the release of ACTH from the AP?
Corticotropin releasing hormone (CRH)
What inhibits CRH?
Glucocorticoids
What secretes CRH?
Hypothalamus
CRH is secreted in response to what?
Stress
Which part of the adrenal gland produces corticosteroids?
Adrenal cortex
Corticosteroids are divided into _________________ and __________________.
Mineralocorticoids and glucocorticoids
What is the main mineralocorticoid (causes water retention)?
Aldosterone
hydrocortisone = ?
cortisol
Which part of the adrenal gland secretes epinephrine and norepinephrine?
Adrenal medulla
Which glucocorticoid regulates important Cardiovascular, metabolic, immunologic, and homeostatic functions?
Cortisol
Adrenal insufficiency can cause:
- hypotension
- shock
- death
Is cortisol catabolic or anabolic?
Catabolic - breaks protein down
What is the effect of cortisol in high levels to the immune system?
Depresses the immune response
ACTH travels to the adrenal gland to stimulate the secretion of?
Glucocorticoids
Dehydroepiandrosterone (DHEA) is secreted by the ?
Adrenal cortex
DHEA is converted into _______ and ___________
Testosterone and estrogen
