AnP Chapter ? (LO6) Flashcards
Skin
Only 1 to 2mm thick in most places, largest organ 17-20sqft
Defines the body’s structure
Self-regenerating tissue
Separates the internal from external environment
Protects the body from invasion by harmful substances
Helps maintain homeostasis
Sensory nerve receptors gather info from outside world
Ability to stretch and flexibility permit freedom of movement
Can signal diseases or disorders in other body systems
EPIDERMIS
Outermost layer
Consists of stratified squamous epithelial tissue
Contains no blood vessels
Obtains oxygen and nutrients by diffusion from dermal layer beneath it
DERMIS
Inner, deeper layer composed of connective tissue
Primarily fibers but also contains elastin fibers and reticular fibers (binds the 2 together)
Contains an abundance of blood vessel, sweat glands, sebaceous glands and nerve endings
Hair follicles
HYPODERMIS
Beneath skin
Subcutaneous tissue
Loose connective tissue and adipose tissue
Subcutaneous fat
hypodermis composed mostly of adipose tissue
Helps insulate the body from outside temp changes
Acts as an energy reservoir
LAYERS OF THE EPIDERMIS
Consists of 4-5 layers and an extra layer in areas with wear and tear
Cells of epidermis outer layer are replaced with new cells
New cells are created in lowest level of the epidermis
The new cells go through changes until they reach skin’s surface
Stratum basale (basal layer) also called stratum germinativum
Innermost layer
Consists of a layer of columnar stem cells
Those stem cells undergo mitosis, producing new skin cells pushing older towards surface
Keratin
tough, fibrous protein
produced when cells are pushed upward and stop dividing
it replaces the cytoplasm and nucleus in each cell
cells flatten and die as they move further away from blood supply
stratum corneum
Outermost layer
Keratin is all that’s left of the dead cells
Consists of up to 30 layers of dead, flat, keratin coated cells
Makes skin surface durable and resistant to abrasions
Effective barrier, preventing h20 from entering body while still allowing evaporation
Keratinocytes
newly arriving flattened cells replace dead cells that flake
Melanocytes
produce melanin, scattered throughout basal layer of epidermis
Melanin
accumulates in cells of epidermis
2 TYPES OF MELANIN
Reddish pheomelanin
Brown-black eumelanin
Skin color is determined b
the amount and type of melanin not melanocytes
how melanin works
Melanocytes release melanin with the help of long projections
Keratinocytes bring the melanin into their cells
Caps of melanin are formed over the top of the cell nucleus to protect from UV rays
Prolonged exposure to sunlight stimulates cells to secrete more melanin
—Protects cell’s nucleus and darkens the skin
Cyanosis
-Blue tint
A deficiency of 02 in circulating blood
jaundice
- yellow discoloration of skin and the whites of the eyes
- Impaired liver function that allows bile to accumulate which stains the skin
Bronzing
A golden brown skin color
A deficiency of hormones from adrenal gland, such as occurs with Addison disease
Albinism
Extremely pale skin, white hair and pink eyes
A genetic lack of melanin
Erythema
Abnormal redness
Increased blood flow in dilated blood vessels close to skin surface
May result from heat, exercise, sunburn or emotions