Anorexia Nervosa Flashcards

1
Q

Anorexia nervosa (AN)

A

Anorexia nervosa (AN) = an eating disorder characterised by abnormally low body weight, a fear of gaining weight and a distorted perception of weight / body image.

  • It accounts for 10% of all eating disorder cases.
  • Onset is normally in adolescence or early adulthood.
  • Of those with AN, 50% ‘recover’, 30% improve, 15% remain chronically ill, 5% die from complications and suicide.
  • Males now account for 25% of reported anorexic cases and are at a higher risk of death, as they are often diagnosed later.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Signs and symptoms

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Concomitant symptoms / complications:

A
  • Gut dysbiosis and low HCL levels.
  • Food intolerances.
  • Low absorption capability.
  • Reproductive problems and menstrual irregularities.
  • Poor immunity.
  • Dentition problems.
  • Anaemia and low mineral levels.
  • Anxiety and depression.
  • Poor skin, hair and nails.
  • Reduced bone mineral density (osteopenia / osteoporosis).
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Anorexia sub-types

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Pathophysiology — biochemical

A

When the body is deprived of the nutrients it needs, changes in brain chemistry and activities can be seen, resulting in:

  • Increased symptoms of depression and anxiety as a result of acute tryptophan depletion.
  • Disruption to cognitive functions.
  • Nerve-related conditions including seizures and numbness or nerve sensations in the hands or feet.
  • Starvation, vomiting, abusing purgatives and laxatives and excessive exercise may lead to dehydration, electrolyte imbalances and low blood potassium levels which will induce psychological problems.
  • Self-induced vomiting and dehydration cause metabolic alkalosis due to loss of K and Cl, leading to further muscle fatigue and tingling in hands and feet.
  • May ultimately lead to cardiovascular complications.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Pathophysiology — serotonin / oestrogen link

A
  • Aromatase is expressed in adipose tissue.
  • Adipose tissue is a key site for the peripheral production and metabolism of oestrogen.
  • Oestrogen deficiency may cause a decline in serotonin through a decrease in density of 5HT 2A receptors and lower activity of serotonin.
  • Low serotonin adds to symptoms of low mood, anxiety, insomnia / sleep disturbances, OCD, migraines and IBS.
  • Carbohydrate consumption, acting via insulin secretion and the plasma tryptophan ratio increases serotonin release
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Clinical diagnosis:

A
  • Intense fear of gaining weight / a healthy BMI.
  • BMI 17.5 or under (combined with other factors)
  • Body dysmorphia.
  • Denies weight is an issue.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Diagnosis — when to suspect an eating disorder

A
  • When a client with an already low BMI approaches you wanting to lose weight.
  • Clients with low BMI that come for amenorrhoea issues, with a fear of fat-containing foods.
  • Young girls in high risk and elite sports who cannot maintain their energy and body weight.
  • Caution: Atypical anorexia shares many features of ‘typical’ anorexia, but without extremely low body weight.
  • Wearing baggy clothing, a jumper etc., even on warm days. This often indicates hiding the body (body dysmorphia) or temperature dysregulation.
  • Angular cheilitis — iron, B12, B2 deficiencies.
  • Dark circle under the eyes — iron deficiency and kidney Qi depletion.
  • Pallor or yellowing to skin tone — anaemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Orthodox medical treatment:

A
  • Re-feeding in hospital or as outpatient.
  • Psychological support.
  • Intense dietary re-training.
  • Anti-depressant medications.
  • Oestrogen replacement therapy (OCP) in women with amenorrhoea.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Orthodox treatment — refeeding

A
  • Refeeding programmes are used to restore BMI.
  • Using high calorific diet incl.

milk, butter and cream.

  • Behavioural reward systems are used to encourage finishing prescribed meals.
  • In serious cases naso-gastric feeding may be required but this requires either permission from the patient or sectioning under the Mental Health Act 5
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Nutrient deficiencies
Zinc
Mg

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Nutrient deficiencies
Tryptophan
Protein
Omega 3
B vitamins

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Nutritional therapy approach

A
  • When working with the anorexic mindset, always work as part of an integrated team and gain client permission to openly share feedback.
  • There may be 3 people in the consultation:
  1. You.
  2. The client.
  3. The condition.
  • Nutritional advice, however well meant, can be dangerous, if you are talking to the condition and not the client.
  • Feeding the brain is a priority.
  • Building a rapport and gaining trust.
  • Communicate appropriate nutrition messages.
  • Help to redefine the relationship with food.
  • Place emphasis on nutrients and health, and not kcal and weight.
  • Correct nutritional deficiencies.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Anorexic consultation

A

AN clients will know much more about the calorie content of foods than you ever will, even with your training: * Do not enter into any conversations around this. Foods that are nutrient or fat dense are often thought of as ‘bad’.

  • Keep focus upon nutrients and their impact upon health.
  • Re-introduction of all foods is essential, even chocolate and other high fat foods should not be discouraged.
  • Never recommend any form of exclusion diet ― e.g., gluten or dairy, unless there is clear evidence that they are detrimental to health.
  • You may have to contain your own self-beliefs, as usual dietary advice will need setting aside to avoid collusion with client

.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Therapeutics — weight gain

A
  • The traditional recommended weight gain for a recovering anorexic of 0.5–1 kg per week is totally unrealistic.
  • This equates to 3500–7000 extra calories a week!
  • Take care if agreeing a calorific target with your client as you may be ‘capping’ food intake. An anorexic will rarely eat 1510 kcal, if you have recommended 1500.
  • Collaborate with the client to create step-by-step changes to the food plan which are moving them to a more diverse range of foods. Remain aware of the client tendency to control the situation.
  • Be wary of weighing clients, as others in the recovery team may already be doing this. Focus on health and not simply BMI.
  • An anorexic’s defence mechanism to change, may be to tell you what they think you want to hear, or to conceal and hide reality ― this usually stems from fear.
  • Be empathetic, but stay firm and consistent with your recommendations.
  • Never try to ‘trick’ or lie about nutritional content of foods. They need to develop trust in the relationship with you and their body.
  • Keep things simple: Do not overwhelm your client with huge changes but focus on 1‒2 changes at a time.
  • From a TCM perspective, Spleen Qi deficiency is common so use foods that are warming, well cooked and nourish the Spleen (focus on slow cooked and warm foods). Focus on nutrient dense foods.
  • Digestive support is often needed to enable nutrient liberation / absorption. Include digestive aids such as well as probiotics for a few months. appetite:
  • Fat deficiency is common — introduce foods that contain essential fats, and limited saturated fats to support reproductive function.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Therapeutics — re-establishing healthy eating:

A
  • Many anorexics no longer feel hunger as they are so ‘disconnected’ from their bodies and their physical needs.
  • Some negotiation is needed to gain agreement for small, regular meals a day — aiming for 3 meals and 2‒3 snacks a day; although this is often not achievable in the early days!
  • Focus on energy and nutrient dense foods, high in calories.
  • Co-create the plan together but be firm about structure.
  • Acknowledge ‘fear’ foods but aim to expand list of ‘safe’ foods.
  • Only ask for a food diary if necessary and no other therapist is requesting one. These can simply keep the focus upon food.
  • When food is restricted, metabolism reduces to prioritise available energy towards major organs, to maintain body functions in the face of starvation.
  • When recovery begins, the body increases metabolism as available energy is made available.
  • There often follows a period of ‘hypermetabolism’, where the body utilises new, additional energy to compensate for huge amount of damage, repair and development.
  • The amount of daily intake therefore needed to gain weight can be incredibly distressing to the eating disorder voice
17
Q

Therapeutics — high calorie / nutrient dense foods:

A
  • Nut butters: 1 tablespoon ― 170–200 calories.
  • Avocado: 1 whole ― 320 calories.
  • Quinoa ― 222 calories per cooked cup.
  • Granola.
  • Protein flapjacks.
  • 1 egg ― 78 calories.
  • Omega-3 fish (e.g., salmon)
  • Natural yoghurt.
  • Glass of whole milk ― 150 calories.
  • Glass of soy milk ― 100 calories.
  • Dips such as hummus made with olive oil or guacamole can be good to add to a sandwich or dinner (e.g., for healthy fats).
  • Oily fish — contains an abundance of readily available nutrients / energy and is high in EPA / DHA.
  • Eggs — a great source of absorbable protein, but they are generally quite filling.
  • Fruit and vegetables are important, but you will find most anorexics already eat a lot of the low-calorie ones! Introduce sweet potatoes, pumpkin, potato and other energy dense foods. Also increase good sources of plant protein, e.g., beans and pulses
18
Q

Therapeutics — re-feeding syndrome

A
  • During starvation, insulin levels decrease and glucagon levels increase, resulting in the conversion of glycogen to glucose and the stimulation of gluconeogenesis, which involves the synthesis of glucose from lipid and protein breakdown products.
  • Subsequent refeeding after starvation causes an increase in insulin release and an increased shift of phosphate, glucose, potassium, magnesium, and water to intracellular compartments often resulting in oedema (i.e., pulmonary) after fluid administration.
19
Q

Therapeutics — supplements

A
  • These need to address any nutrient deficiencies and feed the brain. These are vital to recovery.
  • This proves challenging whilst food is restricted.
  • Whilst food should be the focus in any eating disorder patient, when used wisely, supplements can help to reduce anxiety, improve sleep, increase energy and speed recovery.

See earlier section on common nutritional deficiencies in AN.

  • However, if introduced too soon, the anorexic voice may see supplements as a replacement to food.
20
Q

Therapeutics — zinc:

A
  • It is suggested that zinc therapy enhances the rate of recovery in anorexia nervosa patients by increasing weight gain and improving their levels of anxiety and depression.
  • On the basis of these findings and the low toxicity of zinc, zinc supplementation should be included in any therapeutic protocol for anorexia nervosa.
  • Oral administration of a minimum of 14 mg of elemental zinc daily for 2 months for all AN clients should be routine — vitamin B6 will enhance absorption

Zinc supplementation in re-feed

procedures can be used as an adjuvant intervention, as research is beginning to show that even with as little as 15 mg a day, there is a quicker recovery time.

  • In an open trial of 20 AN females taking 45‒90 mg of zinc (zinc sulphate) daily, all 20 maintained their weight gain at an 8 and 56month follow-up; none developed bulimia
21
Q

Therapeutics — probiotics

A
  • Probiotics — studies have suggested yoghurt with the strains L. bulgaricus and S. thermophilus should be used in the refeeding procedures, as trials have shown an increase in immune markers
22
Q

Therapeutics — L-arginine

A

L-arginine — shown to increase production of platelet nitric oxide (NO) and decrease Ca²⁺ levels in AN clients, while supplementation of L-arginine at a dose of 8.3 g per day for two weeks with no adverse effects. This gives credence to the use of L-arginine in the use of eating disorders to protect against cardiovascular risk factors.

23
Q

Therapeutics — stress / anxiety / depression:

A
  • Identify the cause of any stress / anxiety / depression and address appropriately.
  • Support the nervous system, e.g.:

– Anxiolytics, e.g., passionflower, chamomile, ashwagandha.

– Serotonin support e.g., tryptophan, magnesium, B3, B6, B9, zinc; reduce stress, probiotics, breathing exercises, St John’s wort.

  • Hypercortisolemia is common in AN — consider adrenal support. For example, stress management strategies, adaptogens, B vitamins, magnesium, L-theanine etc.
24
Q

Therapeutics — Bach flowers

A
  • Crab apple helps with body image, body shame, and low self-esteem.
  • Cherry plum helps with a fear of losing control around food.
  • White chestnut helps with obsessive thinking about food.
  • Star of Bethlehem helps process past traumatic events
  • Rock water helps moderate unrealistic standards of perfection.
  • Aspen helps eradicate feelings of anxiety or of impending doom.
  • Elm helps eliminate feelings of overwhelm, such as anxiety
  • Gentian helps people overcome feeling down after a setback.
  • Gorse helps people feelings of hopelessness and suicidal tendencies.
25
Q

Therapeutics — tissue salts:

A

(e.g., New Era, 1 tab 3 x daily for 3–6 months).

  • Calc. phos. — due to poor absorption, weakness and prostration physically and mentally.
  • Nat. mur. — helps improve dry skin, fluid movement within the body and improves hypochlorhydria.
  • Kali. phos. — when there are states of depletion, especially within the nervous system. There may be great anxiety present.

You can take then individually or combine all three as the requirements seem fit.