Animal Form and Function- { The Endocrine System] Flashcards
What is the purpose of the Endocrine System?
The endocrine system produces HORMONES that help maintain homeostasis and regulate reproduction and development.
Endocrine-
synthesize and secretes hormones into bloodstream.
Exocrine
Secrete substances into ducts(Ex - Gall Bladder) (Pancreas is both exo and endo)
Protocrine
Autocrine -
Protocrine -Cell signaling where target is nearby.
Autocrine - is cell signaling via hormone/chemical messenger that binds to receptors or same cell.
Prostaglandins
Causes contraction/relaxation.
They are local regulators that promote inflammation and sensation of pain in response to injury.
General characteristics of hormone:
They are transported throughout body in blood ; small amount = large impact; slower effect.
Hormone Types
- Peptide
- Where is it manufactured and where do it end up?
- Describe some peptide hormones
Synthesized in rough ER and modified in Golgi, acts on surface receptors
-Manufactured in rough ER—->clevages in ER lumen —–> Final form is in Golgi.
They include (AP) FSH, LH, hGH, TSH, prolacting; glucagon, insulin
Hormone Types
- Steroid
- Where are they made?
- Hydrophobic or hydrophillic?
- Synth’d from cholesterol in smooth ER; hydrophobic = freely difuse but require protein transport molecule to dissolve in blood.
Hormone Types
-Tyrosine Derivatives -how is it formed?
Thyroid hormones?
Catecholamines(epi and norepi)
Tyrosine Derivatives - Formed by enzymes in cytosol or on rough ER.
Thyroid Hormones - lipid soluble, require protein from blood
Catecholamines - formed in adrenal medulla; epi and norepi.
Hypothalamus
- NEUROSECRETORY
- PITUITARY GLAND
- INHIBITING HORMONES
- OXYTOCIN/ ADH
Monitors the external environment and internal conditions of the body. Contains NEUROSECRETORY cells that link the hypothalamus to the PITUITARY GLAND. Regulation of the pituitary = negative feedback mechanisms by secreation of releasing and INHIBITING HORMONES. Secretes ADH and OXYTOCIN to be stored in posterior pituitary; also secretes GnRH from neurons, which stimulates anterior pituitary to secrete FSH and LH
Hypothalamus
-Anterior Pituitary -
Gland: Anterior Pituitary
Hormone: GH
Action: Cell Growth
Hypothalamus
- Anterior Pituitary - TROPIC HORMONES
- ACTH
- TSH(Thyroid-stimulating hormone)
- LH -(females)- corpus luteum, Males
- FSH -(males and females_
Anterior Pituitary(TROPIC HORMONES) = stimulate other endocrine glands.
ACTH - Target: Adrenal Cortex
Action: Secretion of glucocorticoids
TSH(thyroid-stimulating hormone) -
Target:Thyroid
Action:Secretion of T4 and T3
LH-
Target: Ovaries, testes
Action: Regulates oogenesis & spermatogenesis
FSH (Follicle stimulating hormone) =
Target: ovaries, testes
Action: regulates oogenesis & spermatogenesis
Posterior Pituitary- does it or does it not make hormones? What does it store?
Does not synthesize hormones, STORES ADH and oxytocin produced by hypothalamus.
Posterior Pituitary-
hormone?
Action?
Target: Kidneys, mammary glands
Hormone: ADH(antidiuretic)
Action: Increases reabsorption of water
- Collecting duct –> water reabsorption and increased blood volume and pressure. Coffee blocks ADH.
- Oxytocin - secreted during childbirth - increases strength of uterine contractions and stimulates milk EJECTION
Pineal Gland -
Hormone: melatonin.
Action: role in circadian rhythm(internal clock).