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Meds For CSO Exam > angiogenesis inhibitors > Flashcards

angiogenesis inhibitors Flashcards

1
Q

What does an angiogenesis inhibitor do?

A

hinders the formation of new blood vessels in tumors

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2
Q

Common side effects of angiogenesis inhibitors

A

HTN, MI, stroke, proteinuria, hemorrage, GI perforation, hypothyroidism

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3
Q

Types of angiogenesis inhibitors

A

Bevacizumab (avastin)-blocks VEGF receptor–> colorectal, NSCLC, glioblastoma, renal

Lenalidomide (revlimid)- inhibits pro-inflammatory cytokines–>MM, MDS

Thalidomide- inhibits pro-inflammatory cytokines –> MM, MDS

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4
Q

Thalidomide (thalomid)

A

PO

Interactions: with barbiturates, alcohol, chlorpromazine, reserpine

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Meds For CSO Exam (14 decks)

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