Angina Treatment Flashcards
Vasospastic angina
Rest angina/ prinzmetal’s angina.
Reversible spasm of coronaries
Atherosclerotic angina
Atheromatous plaques partially occluding coronary arteries.
Classic angina, angina on effort.
Levilles sign
Unstable angina
Crescendo angina, acute coronary syndrome,
Atherosclerotic plaques, platelet aggregation, vasospasm
Therapeutic goals in angina
Increase oxygen delivery.
Decrease oxygen demand
Vasodilators
Nitrates, CCBs
Nitrates
Amyl nitrate
Ultra-short acting nitrate
Increases NO, CGMP, relaxes smooth muscle
Antidote for cyanide poisoning
Cyanide affects
Complex IV of ETC
Antidote cyanide poisoning
Inhaled amyl nitrite IV Na nitrite, IV Na thiosulfate
Monday disease
Occupational exposure to nitrates
Nitroglycerin
Isosorbide dinitrate, isosorbide mononitrate
Short acting
Headaches in nitrates
Throbbing headache due to meningeal artery vasodilation
CCBs
Nifedipine, verapamil, diltiazem
Non-DIHYDROPYRIDINE
Verapamil, diltiazem
Cardiac > vascular
Used for SVT, Reynauds
Drugs that induce gingival hyperplasia
NapaCa Pangit ng gingiVa mo
Nifedipine, Cyclosporine, Phenytoin, Verapamil
Beta blockers
Propranolol