Adrenoceptor Blocker

Question 0

Phenoxybenzamine

Answer 0

Irreversibly blocks a adrenergic a1>a2

Pre-operative treatment pheochromocytoma

Question 1

Nonselective alpha blockers

Answer 1

Phenoxybenzamine, PHENTOLAMINE

Question 2

PHENTOLAMINE

Answer 2

Reversibly blocks a adrenergic receptors a1>a2
Post-surgical therapy for pheochromocytoma
Antidote for rebound hypertension to clonidine

Question 3

Selective a1 blocker

Answer 3

PRAZOSIN, doxazosin, terazosin, tamsulosin, silodosin
BPH HPN
Give at night to prevent orthostatic hypotension

Question 4

Non-selective beta blocker.

Answer 4

Propranolol, pindolol, timolol, labetalol, carvedilol, nadolol.
Reduces renin release.
Adrenergic antagonist

Question 5

Beta-blocker with combined a and b blockade. Can mask symptoms of hypoglycemia.

Answer 5

Labetalol

Question 6

Beta-blockers with ISA intrinsic sympathomimetic activity

Partial agonist, in asthma patients less likely to cause bronchospasm.

Answer 6

Pindolol, acebutalol

Question 7

Beta-blocker with longest half-life

Answer 7

NADOLOL NAsa DOLOL

Question 8

Beta blocker with shortest half life

Answer 8

ESMOLOL esmall

Question 9

Selective beta1 blocker

Answer 9

BeEs Ace MeAt
Betaxolol, ESMOLOL, Acebutolol, metoprolol, ATENOLOL
SVT ESMOLOL only

Question 10

Flow of aqueous humor

Answer 10

Ciliary body –> posterior chamber –> anterior chamber angle –> pupil –> anterior chamber –> trabecular meshwork –> canal of schlemm –> uveoscleral veins

Question 11

SANS on pupil

Answer 11

Dilates

Question 12

PANS on pupil

Answer 12

Constricts

Question 13

Decreases aqueous secretion from ciliary body

Answer 13

Timolol, mannitol, apraclonidine, acetazolamide, dorzolamide

Question 14

Ciliary muscle contraction, opens trabecular meshwork, increases outflow

Answer 14

Pilocarpine, physostigmine

Question 15

Increases aqueous outflow through canal schlemm

Answer 15

Latanoprost

Question 16

Increased outflow from uveoscleral veins

Answer 16

Epinephrine