Androgens Flashcards
1
Q
Androgens
A
- produced by the testes, ovaries, and adrenal cortex
- major endogenous androgen is testosterone
- noted most for their ability to promote expression of male sex characteristics
2
Q
Basic categories of Androgens
A
- testosterone and testosterone esters
- 17-alpha-akylated compounds
3
Q
Therapeutic uses of Androgens
A
- male hypogonadism
- replacement therapy
- delayed puberty
- breast cancer
- replacement therapy in menopausal women
- Wasting in patients with AIDS
- Anemias
4
Q
Adverse Effects of Androgens
A
- virilization
- premature epiphyseal closure
- hepatotoxicity
- effects on cholesterol levels
- uses in pregnancy
- prostate cancer
- edema
- gynecomastia
- abuse potential
5
Q
Anabolic Steroids
A
- used by many athletes to enhance athletic performance
significant risks include hypertension, suppression of release of LH and FSH, testicular shrinkage, sterility, gynecomastia, acne, reduction in HDL and increase in LDL, hepatotoxicity, renal damage, and increased aggression
