Aminoglycosides

Question 1

Aminoglycosides

Answer 1

• extremely potent bactericidal antibiotics that are usually reserved for serious or life-threatening infections
• most commonly used include GENTAMICIN, amikacin, and tobramycin
• only used on gram - organisms
• commonly used with other antibiotics like penicillins, cephalosporins, & vancomycin

Question 2

Aminoglycoside Side Effects

Answer 2

• serious toxicities such as nephrotoxicity, neurotoxicity, ototoxicity, & hypersensitivity

Question 3

Aminoglycoside Absorption

Answer 3

• poorly absorbed from an intact intestinal tract but rapidly absorbed parenterally, also comes in some topical preparations
• no pill form