Anatomy Brain Flashcards
Embryologically, what are the 3 primary swellings that form the brain?
Prosencephalon
Mesencephalon
Rhombencephalon
In the vast majority of people the RIGHT/LEFT cerebral hemisphere is most dominant?
Left
The frontal lobe includes the PRE/POST central gyrus?
Pre-central gyrus
The PRE/POST central gyrus contains the primary somatosensory cortex?
POST central gyrus
The PRE/POST central gyrus contains the primary motor cortex?
PRE central gyrus
- go (motor) to pres
Where is Broca’s area located?
Frontal lobe (within the inferior frontal gyrus)
Where is Wernike’s area located?
Temporal lobe (within the superior temporal gyrus)
What is the function of Broca’s area?
Producing speech
Also responsible for writing
What is the function of Wernike’s area?
Understanding language
Damage to Broca’s area results in?
Expressive dysphasia
- patient can understand words
- patient can’t produce sound sentences
Damage to Wernike’s area results in?
Receptive dysphasia
- patient can’t understand words
- patient can speak fluently
Name the main functions of the frontal lobe?
Movement (pre-central gyrus) Producing speech (Broca) Personality, behaviour, emotions Judgement, planning, problem solving Concentration Intelligence
What lobe of the brain is important for personality?
Frontal lobe
Which lobe of the brain contains the post-central gyrus?
Parietal lobe
What is the post-central gyrus responsible for ?
Contains the primary somatosensory cortex
What is the function of the parietal lobe?
Processes sensory information such as taste, temperature, touch
Damage to the parietal lobe results in?
Unable to feel sensations of touch
What lobe of the brain is responsible for decision making and planning?
Frontal lobe
What lobe of the brain is responsible for processing auditory information?
Temporal lobe
Where is the auditory area of the cortex?
Superior temporal gyrus
What lobe of the brain is responsible for processing visual information from the eyes?
Occipital lobe
Damage to the occipital lobe results in?
Unable to correctly process visual signals
What is the function of the insular lobe?
Important role to play in patient’s experience of pain
Left hemisphere of the brain functions (*for right handed individuals)
Speech
Motor
Sensory functions
Right hemisphere of the brain functions (*for right handed individuals)
Abstract concepts
Which lobe is the lesion in?
- Receptive dysphasia
- Seizures
- CN III palsy
Temporal lobe
Which lobe is the lesion in?
- contralateral motor weakness
- personality changes
- expressive dysphasia
Frontal lobe
Which lobe is the lesion in?
- visual hallucinations
- contralateral homonymous hemianopia
Occipital lobe
Which lobe is the lesion in?
- contralateral sensory loss
- difficulty understanding maths
- difficulty writing
- left right disorientation
Parietal lobe
What are the 3 components of the brainstem?
Midbrain
Pons
Medulla oblongata
What does a cross section of the midbrain look like?
Mickey mouse
What does a cross section of the pons look like?
Stripey (transverse pontine fibres)
What does a cross section of the medulla look like?
Wiggly worms
Where is the olivary nucleus located?
Medulla
What is the function of the midbrain?
Motor movements
- particularly movements of the eye and in auditory and visual processing
What is the function of the pons?
Relays information from the cortex and the cerebellum
What is the function of the medulla?
Carries out and regulates life sustaining functions such as breathing, swallowing and heart rate
Gyrus
Bumps on the surface of the brain
Sulcus
The slits (depressions) in the brain)
What is the importance of the central sulcus?
It divides the precentral gyrus (motor) from the post central gyrus (sensory)
In which lobe of the brain is the calcarine sulcus located?
Occipital lobe
The internal capsule is a GREY/WHITE matter tract?
White matter tract
What is the function of the internal capsule?
It carries information towards the brainstem
Where is the corpus callosum located?
Near the lateral ventricles
What is the function of the corpus callosum?
Carries information from left to right hemisphere
In the brain, grey matter is the INNER/OUTER aspect?
Outer
In the brain, white matter is the INNER/OUTER aspect?
Inner
Neurones are located in the WHITE/GREY matter?
Grey
Axons are located in the WHITE/GREY matter?
White
Cell processes are located in the WHITE/GREY matter?
Grey
What is the function of meninges?
Protective coverings for the brain and spinal cord
What are the 3 meninges?
Dura matter
Arachnoid matter
Pia matter
Dura matter - layers
Periosteal layer (superficial) Meningeal layer (deep) These 2 layers are usually stuck to each other but sometimes they split and a channel forms between them known as the dural venous sinus.
What is the diaphragm sellae
Tough sheet of dura mater forming a roof over the pituitary fossa
What is the tentorium cerebelli
Sheet of dura matter which acts as a tent over the cerebellum, separating the cerebellum from the occipital lobe
What is the fall cerebri
Sheet of dura matter in the midline which separates the right and left cerebral hemispheres
Appearance of arachnoid matter
Spidery
Outpouchings (granulations)
What is the function of arachnoid granulations?
Facilitate the recycling (resorption) of CSF
Where is circulating CSF located?
Subarachnoid space (between arachnoid and pia matter)
Pia matter appearance
Very thin and shiny surface
Pia matter location
Directly adherent to brain tissue - follows the contours of the brain closely
Where is CSF produced?
Choroid plexus (located in the ventricles of the brain)
Ventricular pathway in the brain
Lateral ventricles (C-shaped)–> interventricular foramen of Monroe –> 3rd ventricle –> cerebral aqueduct –> 4th ventricle
Location of the 3rd ventricle
In the midline between the right and left halves of the diencephalon
Location of the 4th ventricle
Between the cerebellum and pons
Name 2 locations where CSF is absorbed?
Subarachnoid space
Central canal of SC
Name 1 location where CSF is recycled
Arachnoid granulations
What is the anastomotic blood supply of the brain and where in the brain is it located?
Circle of willis
Subarachnoid space
Anterior circulation of the brain originates from ?
Internal carotid arteries
Posterior circulation of the brain originates from ?
Vertebral arteries
The anterior circle of willis is formed by which arteries?
Posterior cerebral Posterior communicating Internal carotid Anterior cerebral Anterior communicating
R and L vertebral arteries join to form ?
Basilar artery
Basilar artery splits to form ?
R and L posterior cerebral artery
What supplies the posterior aspect of the cerebral hemispheres including the occipital lobe?
Posterior cerebral arteries
What is the function of the posterior communicating artery?
Connects the anterior and posterior circulations (branch of ICA and branch of posterior cerebral artery)
What gives rise to ophthalmic arteries?
ICA
ICA gives rise to middle cerebral arteries. True or False?
True
What arteries supply the lateral aspect of the cerebral hemispheres?
Middle cerebral arteries
What does middle cerebral arteries give rise to?
Anterior cerebral arteries
What arteries supply the medial aspect of cerebral hemispheres?
Anterior cerebral arteries
What is the main venous drainage network of the brain?
Dural venous sinuses
The superior and inferior sagittal sinus is located where?
In the Falx Cerebri
Pathway of venous drainage in the brain
Superior/inferior sagittal sinus –>
confluence of sinuses –>
Sigmoid sinus –>
IJV –> IJV leaves skull through jugular foramen
What passes through the cavernous sinus?
Internal carotid artery CN III CN IV CN V1 CN V2 CN VI
Components of the diencephalon
Thalamus
Hypothalamus
Thalamus - function
Modulates motor function by having connections with the motor cortex, basal ganglia and cerebellum
Hypothalamus - function
Thermal regulation
Regulates hormone release
Regulates feeding and starvation
Where is the cerebellum located?
Inferior to the cerebral hemispheres
Tentorium cerebelli separates the cerebellum from the cerebrum
Function of the cerebellum
Balance and coordination of muscles and the body
An intended movement occurs in motor cortex.
Cerebellum helps corticospinal tract plan that movement then the movement occurs.
Cerebellum signals to the thalamus to alter the movements to ensure they are smoothly executed
The cerebellum has 2 hemispheres that are united by which narrow midline structure?
Vermis
What lobes are present in the cerebellum?
Anterior
Posterior
Flocculonodular
The cerebellum contains sulci and gyri - true or false?
False
it contains sulci and folia
What is the deep cerebellar nuclei?
Grey matter found deep in the white matter core
What are peduncles?
White matter tracts that attach the cerebellum to the brainstem
What are the 3 cerebellar layers
Molecular layer (outer)
Purkinje cell layer (middle)
granule cell layer (inner)
Sensory inputs to the cerebellum enter cerebellar peduncles and project to which cerebellar layer?
Granule layer
The only motor output from the cerebellum is from which cell layer?
Purkinje cells
Cerebellar dysfunction symptoms - pneumonic
Dysdiadochinesia Ataxia Nystagmus Intention tremor Scanning dysarthria Hypotonia
Basal ganglia is an essential part of the SENSORY/MOTOR system?
Motor
Functions of basal ganglia
Facilitate purposeful movement
Inhibit unwanted movement
Role in posture and muscle tone
Basal ganglia contains a series of WHITE/GREY matter structures?
Grey matter
Name the 5 components of the basal ganglia?
Caudate nucleus Putamen Globus pallidus Subthalamic nucleus Substantia nigra
What are the components of the striatum?
Caudate nucleus
Putamen
What are the components of the lenticular nucleus?
Putamen
Globus pallidus
Which component of the basal ganglia has 2 stripes?
Globus pallidus
How does the basal ganglia work with the motor cortex to enhance normal movement?
Excitation of desired movement +
Inhibition of undesired movement
How does the basal ganglia work with the motor cortex to suppress unwanted movement
Inhibits outflow from the thalamus
Unilateral lesions in the basal ganglia affect the IPSILATERAL:/CONTRALATERAL side of the body?
Contralateral
Lesions in the basal ganglia cause the following motor signs
Change in muscle tone Dyskinesia - tremor - chorea - myoclonus
Which fibres connect cortical sites lying in the same hemisphere?
Association fibres
Which fibres connect one hemisphere to the other (usually connecting areas with similar function)?
Comissural fibres
Which fibres connect hemispheres to deeper structures (eg thalamus, brainstem, SC)
Projection fibres
What are the 5 layers of scalp
Skin Connective tissue Aponeurosis Loose connective tissue Pericranium
Which layer of the scalp contains the main arterial blood supply for the scalp?
Connective tissue
- branches from ECA and ICA
Sutures are cartilaginous joints. True or false?
False
- fibrous joints
What is the function of sutures?
Connect the bones of the skull
Helps prevent skull fractures from spreading to other bones
What is the pterion?
H shaped suture where all the skull bones (apart from occipital) meet
Which lobe of the brain is responsible for memory?
Temporal lobe
Which lobe of the brain is important for executive function (i.e. making lists)?
Frontal lobe