Anatomy Flashcards
Acidophilic Normoblasts
Formed from polychromatic normoblast.
Actin
Protein in muscle fiber; contraction and relaxation.
Actin Filaments
Stabilize cell adherence
Active Transport
ATP energy moves molecules across membrane
Facilitated Transport
Adenosine Triphosphate ATP
Nucleotide transports chemical energy within cells for metabolism.
Converts O2 <span>to CO</span>2
Afferent
Leading towards organ
Adherens Junctions
Strong mechanical attachments between adjacent cells.
Polychromatic Normoblast
Forms basophilic normoblast
Starts to make hemoglobin
No longer divider
Arrector Pili Muscle
Small, involuntary muscles in the base of hair follicle that cause goose flesh when appendage contracts, sometimes called goose bumps and papillae.
Apocrine Glands
Coiled structures attached to hair follicles found in the underarm and genital areas that secrete sweat.
Amino Acids
Organic Acids- form binding blocks of proteins
Ceramides
Glycolipid materials that are a natural part of skin’s intercellular matrix and barrier function.
Collagen
Fibrous, connective tissue made from protein; found in reticular layer of dermis; gives skin its firmness. Topically, a large, long chained molecular protein that lies on top of skin and binds water; derived from placentas of cows or other sources.
Stratum Granulosum
Granular layer.
Composed of cells filled with keratin that resemble granules.
Replaces cells shed from stratum corneum.
Corneocytes
Stratum corneum cell; hardened, water-proof protective keratinocytes; these “dead” protein cells are dried out and lack nuclei
Dermis
Also known as derma, corium, cutis, or true skin.
Support layer of connective tissue, collagen, and elastin below epidermis.
Eccrine Glands
Sweat glands found all over the body with openings on the skin’s surface through pores; not attached to hair follicles. Secretions do not produce an offensive odor.
Lysosome
Contains digestive and hydrolytic enzymes.
Digests foreign matter.
Elastin
Protein fiber found in the dermis; gives skin its elasticity and firmness.
Epidermis
Outermost layer of skin; a thin, protective layer with many cells, mechanisms, and nerve endings. It is made up of 5 layers:
Stratum Corneum
Stratum Lucidum
Stratum Granulosum
Stratum Spinosum
Stratum Germinativum
Eumelanin
A type of melanin that is dark brown to black in color. People with dark colored skin mostly produce eumelanin. There are 2 types of melanin; the other is pheomelanin.
Barrier Function
Protective barrier of the epidermis; the corneum and intercellular matrix protect surface from irritation and dehydration.
Fibroblasts
Cells that stimulate cells, collagen, and amino acids that form proteins.
Follicles
Hair follicles and sebaceous follicles are tube-like openings in the epidermis.
Glycation
Caused by elevation in blood sugar.
Binding of a protein molecule to a glucose molecule resulting in formation of damaged, nonfunctioning structures, known as AGES.
Alters protein structures and decreases biological activity.
G 1
Interphase-active metabolism
Gap 1
Intermediate Filaments
Maintain cell shape, strengthen cells.
Islet of Langerhans Cells of Pancreas
Makes insulin
JNK
Pathway–intermediate siganal of DNA signaling cascade.
Keratin Sulfate
Proteoglycan found in dermis.
Keratin Proteins
Skin and Hair
Resists water and frictions.
Keratinohyaline Granules
Horny and Hyaline
Keratinocytoblasts
Stem cells with low rate of mitosis.
Produce transient amplifying cell.
Leukocytes (white blood cells)
White blood cells that have enzymes to digest and kill bacteria and parasites.
Respond to allergies.
Lipase
Enzyme accelerates hydrolysis or synthesis of fats
Lipid Bilayer
Hydrophilic and Hydrophobic
Epidermal Growth Factor
Abbreviated EGF; stimulates cells to reproduce and heal.
Lymphocyte
WBC, produced by stem cells.
Digests foreign invaders.
Lymphokine
Causes physilogical changes in certain other cells.
Lymphotoxins
Causes cell lysis
MAPK
Pathway used as intermediate signal as part of DNA signaling cascade.
Macrophage
In vertabrates, performs crucial functions in immune response.
Lysozyme
Enzyme that dissolves and digests many biochemicals.
Melanogenesis
Process of making melanin pigment.
Melanocyte Stimulating Hormone (MSH)
Stimulates melanocytes to make melanin.
Melanocyte
Produces pigment granules/melanin in basil layer.
Meissner’s Corpuscles
Transmit touch, pressure, and cold.
Maturation Promoting Factor (MPF)
Initiates parts of mitosis.
Mast Cell
Releases pharmacologically active substances with role in inflammation.
Membrane
Phospholipid bilayer impregnated with protein that is differentially permeable.
Memory T Cells
Recognize and respond to pathogen once it has been invaded and repelled.
Merkel’s Discs
Discriminate touch, shape, and texture.
Mesenchymal Tissue
Embryonic connective tissue.
Mesoderm
Third germ layer.
Gives rise.
Microfilaments
Protein strands made of actin.
Cell movement and shape.
Microtubules
Separate chromosomes during cellular division.
Mitochondria
Conduct cellular respiration
Monocyte
Leukocyte travels in bloodstream and neutralizes pathogens.
Mother Cell
Stem Cell. Capable of Division.
Myclin
Fatty material forming medillary sheath of nerve fibers.
Mycloperoxidase
Enzyme used in killing action of neutrophils.
Myosin
Large protein of contractile tissue. Forms thick myofilaments of striated muscle.
Neural Crest
Early nerve tissue in embryo.
Orgin of melanocytes.
Layer of ectoderm germ layer.
Neural Tube
Layer of ectoderm germ layer.
Provides most of CNS.
Neurofilament
Intermediate filament found in nerve cells.
Neuroglia
Cells that provide support and nutrition to tissues
Neutrophilis
Most abundant polymorphonuclear leukocytes. Phagocytic White blood cells.
Nuclear Membrane
Membrane surrounding nucleous of eukayotic cells.
Nucleolus
Contains RNA
P27 Protein
Binds to cyclin and CDK
Oxytalan
Elastin type fiber found in dermis.
Contains only microfibrils.
10-12 nm in diameter.
P53 Protein
Tumor supressor proteins
Mutation encodes it.
Pacinian Corpuscle
Sensory Receptor
Phagocyte
Any cell that engulfs and devours microorganisms or other particles.
Phospholipids
Compounds that contain fatty acid and phosphoric acid groups
Plakoglobin
1 of 2 proteins that make up plaques.
Pluripotential Stem Cell
Cell at start of blood cell line that is programmed to form all other cells in bloodstream.
Platelet-derived Growth Factor (PDGF)
Growth regulating cytokine
Initiates proliferation of fibroblasts and other connective tissue cells.
Plasma Membrane
Cellular membrane
Plaques
In cell membrane
2 Proteins-desmoplakin and plakoglobin.