Analogue thymidine Flashcards

1
Q

MA

A

Inhibition de la synthèse d’ADN.

Phosphorylation indépendante des kinases virales.

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2
Q

Mono-PO4

A

Inhibe thymidylate synthétase

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3
Q

Tri-PO4

A

Inhibe ADN polymérase, augmente le taux de mutation et mène à la formation de protéines non-fonctionnelles.

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4
Q

Trifluridine
Spectre
Forme

A

Spectre : VHS résistante à ACV, CMV, certains adénovirus.

Forme : Goutte topique.

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