Amiodarone

Question 0

Indications for use of Amiodarone

Answer 0

Treatment of defibrillation-refractory VF/Pulseless VT, polymorphic VT, and wide complex tachycardia
Rate control in atrial fibrillation or flutter

Question 1

Mechanism of action for Amiodarone

Answer 1

Effects on sodium, potassium, and calcium channels
Prolongs action potential, refractory period
Ventricular automaticity
Slows membrane depolarization
Slows down heart rate
Dilates coronary arteries

Question 2

Contraindications of Amiodarone

Answer 2

Bradycardia 
2nd or 3rd degree heart block 
Cardiogenic shock
Hypotension
Pulmonary congestion 
Thyroid disease

Question 3

Adverse reactions of Amiodarone in CV

Answer 3

Bradycardia, hypotension, asystole/cardiac arrest, atrio-ventricular block

Question 4

Adverse reactions of Amiodarone in torsades de Pointes

Answer 4

(Prolongs QT interval) congestive heart failure

Question 5

Adverse reactions of Amiodarone in GI & hepatic

Answer 5

Nausea, vomiting,

Question 6

Adverse reaction of Amiodarone in skin

Answer 6

Slate-blue pigmentation

Question 7

Adverse reaction of Amiodarone

Answer 7

Fever, headache, dizziness, flushing, abnormal salivation, photophobia

Question 8

Administration of Amiodarone

Answer 8

IV/IO bolus, IV/IO infusion

Question 9

Adult dosage of Amiodarone for VF/Pulseless VT

Answer 9

300mg push over 30-60 seconds

May repeat in 3-5 min with 150

Question 10

Adult dosage of Amiodarone for wide-complex tachycardia, atrial flutter and Fib, SVT with cardioversion

Answer 10

150 mg IV over 10 min

May repeat every 10 min