Amino Acids Flashcards
What are proteins
Bio polymers composed of amino acid monomers linked by peptide bonds
Amino acids classifications
Non-polar neutral have hydrophobic R group
Polar neutral have hydrophilic but neutral R groups
Polar acidic have hydrophilic acid R groups ie R groups contains COOH
Polar basic have R groups with basic N group
The secondary, tertiary and quaternary structures of proteins are due to …
interaction between the amino acid side chain residues (-R groups) and the backbone polypeptide chain.
The interactions between –CONH- groups of the peptide chain are responsible for
a-helix conformation and b-pleated sheet conformations in peptides. (secondary structures)
Further interactions between side chain residues are responsible for
tertiary and quaternary structures of proteins.
A-helix elements
Resembles right handed coiled spring
Each peptide bond forms 2 H bonds
B-sheet elements
Almost completely extended poly chain
Backbone forms zigzag
Side chains project above and below sheet structure
B-strands May be aligned parallel or anti-parallel to form b-sheets
What is tertiary and quaternary structure maintained by
Side chains of amino acids