Amines Flashcards
Benadryl contains
Tertiary amine grp
Adrenaline and ephedrine contains
Secondary amine grp
In trimrthyl amine the bond angle is
108°
Toluidine is
Methyl amine
Rn of Fe + HCl is preferred because
FeCl2 formed gets hydrolyzed to release Hcl this only a small amount of Hcl is required To intiate the rn
In ammonolysisi who act as nucleophile
Primary amine obtained by
In ammonolysis primary amine can be obtained by using
Large excess of ammonia
In Hoffmann degradation migration of alkyl grp takes place from
Carbonyl carbon of an amide to nitrogen atom
In Hoffmann degradation 1 Br2 needs
4 NaOH
Lower aliphatic amines are gases with
Fishy oduour
Anneline and other arylamines are colourless but become coloured when they undergo
Oxidation
Tertiary molecules don not have
Intermolecular association due to lack of H atom
Aliphatic amines are stronger bases than
Ammonia
Aromatic aminesa are less basic than
Ammonia
Aliphatic amines are more basic than
Ammonia
In aqueous phase substituted ammines are stabilized by
+I effect and salvation effect the salvation effect
Which is more dtsble anneline or annelium ion
Anneline
Amines on reaction with carnoxylic acids form
Salt at room temp
In acetylation pyridine is used because
To remove HCl formed and to keep equilibrium to right hand side
Isocyanides are
Foul smelljng
Primary amines liberats which gas with NaNO2 +HCl
N2
Distinguishing tests for amines is
Rn with nitrous acid
Hinsberg reagent is
C6H5SO2CL benzene sulphonyl chloride
Is N,N- diethyl benzene sulpjknamide soluble in alkali
Since it does not contain h atom it is not double
Which amines does not react either benzene sulphonyl chloride
3°
These days benzene sulphonyl chloride is replaced by
P- toluenesulphonyl chloride
Hinsberg reagent converts 1° amine to
2°
Is benzene sulphonamide soluble in alkali
The hydrogen attached with benzene sulphonamide is highly acidic in nature due to the presence of strong electron withdrawing sulphonyl grp , hence it is soluble in alkali
Why is meta product formed during nitration of anneline
In strongly acidic medium the anneline is protonated to gorm annelinium ion , which is meta firectingbn hence meta products are Aldo obtained
Why anneline does not undergo Friedel crafts alkylation
Due to salt formation with AlCl3 which is a Lewis acid used in the reaction as catalyst
What is the solubility of benzene diazonium chloride
Soluble and stable when water is cold but reacts with water when warmed
Benzenediazonium fluroborate is
Water insoluble and stable at room temp
Treating the benzenediaxonium with Cu2Cl2/ HX [Cu(I)]is termed as
Sandmeyer reaction
Treating benzeneduazonium with Cu powder / HX is termed as
Gattermann rn
Which has more yield sandmeyer or gattermann
Sandmeyer
When aeene diazonium chloride is heated with fluroboric acid ,arene diazonium fluroborate is precipitated which on heating forms
Aryl fluoride
P- hydroxy azobenzene is
Orange dye
P hydroxy Amino benzene is
Yellow dye
Tertiary amines like trimethyl amine are used as
Insect attractants
