AM- Spectrum of Commonly used agents

Question 1

What are commonly used B-lactam antibiotic agents?

Answer 1

Penicillins

Cephalosporins

Glycopeptides EG vancomycin

Carbapanems

Question 2

What are aminoglycosides commonly used for?

Answer 2

• Action against gram-negative organisms including pseudomonas (lung infections)
• parenteral use only
• Gentamicin is the cheapest and most commonly used

Question 3

How does aminoglycosides and macrolides work?

Answer 3

Inhibition of protein synthesis

Question 4

how does b-lactam antibiotic works?

Answer 4

Disrupt peptidoglycan synthesis by inhibiting the enzymes (penicillin-binding proteins PBPs) responsible for cross linking the carbohydrate chains

Question 5

What are macrolides antibiotics used for?

Answer 5

• Includes Clarithromycin, azithromycin, erythromycin activity is mainly against Gram-positive organisms
• Used as an alternative to penicillin

Question 6

What are quinolone antibiotics used for?

Answer 6

wide spectrum of actin which are active against nearly all gram negative organisms including pseudomonas

Question 7

What are other antibiotics used?

Answer 7

• Triomethoprim
• Tetracyclines (inhibiting protein synthesis)
• Linezolid and Daptomycin