Alcoholic Hepatitis

Question 1

What is alcoholic hepatits?

Answer 1

An inflammatory condition of the liver caused by heavy alcohol consumption.

It can be aggravated by binge drinking.

Question 2

What are some acute complications of alcoholic hepatitis? (2)1

Answer 2

• Seizures

- Renal Failure

Question 3

What are some chronic complications of alcoholic hepatitis? (7)

Answer 3

• Jaundice
• Cirrhosis
• Liver Cancer
• Portal Hypertension
• Varices
• Malnutrition
• Brain Damage

Question 4

What is the prognosis of alcoholic hepatitis? (3)

Answer 4

Pretty poor: 40% mortality (90% if severe)

• If they present with encephalopathy: 64% One Year mortality.
• If they present with deompensating liver disease: 70% Five Year mortality.

Question 5

What are the symptoms of Alcoholic Hepatitis? (6)

Answer 5

• Ascites
• Jaundice
• Encephalopathy
• Dark urine

Maybe:

• Decompensated Hepatic Function
• Infection

Question 6

What is the spectrum of alcoholic liver diesase? (4)

Answer 6

• Normal
• Steatosis
• Hepatitis
• Cirrhosis

Question 7

What investigations do we conduct for people suspected of alcoholic hepatitis? (3)

Answer 7

• LFTs
• Ultrasound of Liver
• CT

Question 8

What LFTs are diagnostic indicators for Alcoholic Hepatitis? (3)

Answer 8

• Raised Bilirubin
• Gamma GT
• Alkaline Phosphate

Question 9

How do we treat alcoholic hepatitis? (5)

Answer 9

• Treat alcohol withdrawal
• Protection against GI Bleed
• Steroids (if Glasgow Alcoholic Hepatitis Score > 9)
• Treat infection and encephalopathy
• Liver Transplant (if they stop drinking!)

Question 10

What nutritional supplement can we give patients with alcoholic hepatitis?

Answer 10

Thiamine

Question 11

What is the Glasgow Alcoholic Hepatitis Score?

Answer 11

Predicts mortality in patients with alcoholic hepatitis by lab results and age.

Question 12

What factors are considered in the Glasgow Alcoholic Hepatitis Score? (5)

Answer 12

• Age
• WBC
• BUN
• Bilirubin
• Prothrombin Time (PT)