Age-Related Changes in Body Composition & Measurement Flashcards

1
Q

what is primary aging

A

unavoidable deterioration of structure and function

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2
Q

what is secondary aging

A

deterioration of structure and function due to preventable lifestyle and environmental exposures

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3
Q

when is secondary aging usually seen

A

in context of disuse that occurs with aging

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4
Q

how can secondary aging be modified

A

through intervention

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5
Q

what can a decline in physiological function with age result in

A

reduced reserve capacity meaning the organs are more vulnerable to stresses

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6
Q

what are age-related changes in the body

A

changes in bone, muscle, and fat tissues with increasing age and accompanying increase in low-grade chronic inflammation

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7
Q

what occurs during the decline in bone mass with aging

A

bone mineral density starts to decline more measurably around 50 YO

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8
Q

females can lose up to what percent of bone mass 5-7 years post menopause

A

20%

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9
Q

what can lead to osteoporosis

A

clinical loss of bone density

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10
Q

what contributes to weaker bone

A

infiltrated fat in the bone

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11
Q

what age does muscle mass peak

A

at 30 years old

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12
Q

what percent does muscle mass decline in 40-50 years old

A

3 - 8%

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13
Q

what is the rate of decline in muscle mass with aging determined by

A

diet and physical activity level

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14
Q

what causes myosteatosis

A

when fat infiltrates the muscle

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15
Q

what can lead to sarcopenia

A

clinical loss of skeletal muscle mass and strength

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16
Q

what does the percentage pf body fat and total mass do with age

A

it increases up until 70-80 years old

17
Q

what type of fat increases with aging

A

increased subcutaneous and visceral fat

18
Q

why is there an increased fat mass in the abdominal region with aging

A

associated with increased risk of metabolic disorders and CV disease

19
Q

where in the body is there an increase in ectopic fat accumulation

A

skeletal muscle, liver, pancreas, and heart

19
Q

what percentage is body weight increased between 25–60-year-olds

A

15%

20
Q

what does TEE stand for

A

total energy expenditure

21
Q

what does BEE stand for

A

basal energy expenditure

22
Q

what is the vicious cycle

A

muscle and bone loss, and visceral fat accumulation with aging combined with an increase in total adiposity

23
Q

what is osteosarconpenic obesity syndrome

A

a multimorbid state that predisposes an individual to further morbidity

24
Q

what occurs when an individual has osteosarcopenic obesity syndrome

A

increased risk of weakness and imbalance, falls, fractures, further decline in function, frailty, and disease

25
Q

what is acute inflammation

A

high-grade immediate response to an injury or trauma (how the body repairs itself)

26
Q

what is chronic inflammation

A

low-grade and is associated with aging and causes damage build-ups

27
Q

what does chronic inflammation promote

A

catabolic state

28
Q

what is catabolic state

A

decreased mitochondrial funciton, muscle fibre atrophy, bone mineral breakdown, and fat redistribution

29
Q

does pro-inflammatory cytokines increase or decrease with age

A

increases

30
Q

centenarians are associated with what levels of pro-inflammatory cytokines and anti-inflammatory cytokines

A

lower levels of pro-inflammatory cytokines and higher levels of anti-inflammatory cytokines

31
Q

what is inflammageing

A

an age-related chronic persistence of pro-inflammatory markers in the blood

32
Q

what is a predictor of morbidity and multimorbidity

A

inflammaging

33
Q

what increases chronic inflammation

A

Osteokines, myokines, and adpiokines

34
Q

what is a DEXA scan

A

a picture of what is going on in terms of tissue distribution like muscle and fat amount and bone density

35
Q

what is the short physical performance battery

A

a well-validated test that is used in institutional and community-dwelling populations of older adults