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Pharm 161 > Adrenergic Blocking Antagonists T-2 > Flashcards

Adrenergic Blocking Antagonists T-2 Flashcards

1
Q

Adrenergic blocking agents prevent?

A

norepinephrine from activating the receptor

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2
Q

Indications for alpha and beta adrenergic blocking agents:

A

essential HTN

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3
Q

Contraindications for alpha and beta adrenergic blocking agents:

A
  • bradycardia or heart block

- shock or CHF

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4
Q

Caution for alpha and beta adrenergic blocking agents:

A
  • bronchospasm
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5
Q

Drug to drug interactions for alpha and beta adrenergic blocking agents:

A
  • enflurane, halothane or isoflurance anesthetics
  • diabetic agents
  • calcium channel blockers
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6
Q

Prototype for alpha and beta blocking agents:

A

Labetalol

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7
Q

Alpha adrenergic blocking agent actions:

A

blocks postsynaptic alpha 1 receptors, decreasing sympathetic tome in vasculature and causing vasodilation

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8
Q

Contraindications for alpha adrenergic blocking agents:

A
  • allergy

- CAD or MI

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9
Q

Cautions for alpha adrenergic blocking agents:

A
  • pregnancy or lactation
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10
Q

Adverse reactions for alpha adrenergic blocking agents:

A
  • hypotension, orthostatic hypotension, angina, MI, CVA

- arrhythmia, weakness, and dizziness

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11
Q

Drug to drug interactions for alpha adrenergic blocking agents:

A
  • ephedrine and epinephrine

- alcohol

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12
Q

Prototype for alpha adrenergic blocking agent:

A

Phentolamine

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13
Q

Alpha 1 selective blockers block the?

A

postsynaptic alpha 1 receptor site

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14
Q

Indications for alpha 1 selective blockers:

A
  • BPH

- HTN

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15
Q

Contraindications for alpha 1 selective blockers:

A
  • allergy

- lactation

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16
Q

Caution for alpha 1 selective blockers:

A
  • CHF

- renal failure

17
Q

Adverse effects for alpha 1 selective blockers:

A
  • dizziness, weakness, fatigue
  • N/V, abdominal pain, diarrhea
  • arrhythmias, hypotension, edema, CHF, and angina
18
Q

Drug to drug interactions for alpha 1 selective blockers:

A
  • vasodilators and antihypertensive
19
Q

Prototype for alpha 1 selective blockers:

A

Doxazosin

20
Q

Indications for beta-blockers:

A
  • treating cardiovascular problems: HTN, Angina, Mirgraine headaches
  • preventing reinfarction after MI
21
Q

Contraindications for beta blockers:

A
  • allergy
  • bradycardia, heart block, shock, CHF
  • COPD, asthma
22
Q

Caution for beta blockers:

A
  • diabetes, hepatic dysfunction
23
Q

Adverse reactions for beta blockers:

A
  • fatigue, dizziness, depression, sleep disturbances
  • bradycardia, heart block, hypotension
  • bronchospasm
  • N/V/D
  • decrease libido
24
Q

Drug to drug interactions for beta blockers:

A
  • clondine
  • NSAIDS
  • insulin or anti-diabetic medications
25
Q

Prototype for beta blockers:

A

propanolol

26
Q

Prototype for beta 1 selective blockers:

A

atenolol

Pharm 161 (10 decks)

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