Adrenaline

Question 1

Class

Answer 1

catecholamine

Question 2

Classification

Answer 2

Sympathomimetic

Question 3

Actions

Answer 3

Stimulates alpha and beta adrenoreceptors

Question 4

Generic Name

Answer 4

Adrenaline/Epinephrine

Question 5

Presentation

Answer 5

Prefill syringe: 1mg/10ml

Ampule: 1mg/1ml

Question 6

Pharmacological Action

Answer 6

• Sympathomimetic that stimulates both alpha and beta adrenoreceptors of sympathetic nervous system.
• Naturally occurring endogenous hormone that increases inotropic, dromotropic and chronotropic effect of cardiac and smooth muscle
• constricts smaller arterioles to regulate blood pressure
• facilitates bronchodilation

Question 7

Pharmacokinetics

Answer 7

• released or interacts at a synaptic level

- metabolised by enzyme monoaminoxidase (MAO)

Question 8

Indication

Answer 8

• cardiac arrest
• anaphylaxis
• life threatening asthma

Question 9

Contra-indication

Answer 9

• Do not give repeated doses of adrenaline in hypothermic patients

Question 10

Cautions

Answer 10

Ischemic heart disease, severe angina and hypertension in patients on non-cardioselective beta-clocker

Question 11

Adrenaline Administration during cardiac arrest?

Answer 11

Administer adrenaline every 3-5 mins

Question 12

Adrenaline administration in Cardiac Arrest - Non shockable rhythm?

Answer 12

Administer adrenaline immediately IV

Question 13

Adrenaline Administration in cardiac arrest - Shockable rhythm?

Answer 13

Administer adrenaline after third shock. If VF/pVT persists, give adrenaline 1mg IV and amiodarone 300mg IV while performing a further 2 min CPR.