ADHD- Bupropion and TCAs Flashcards
1
Q
Bupropion MoA
A
weak DA and NE reuptake inhibitor
2
Q
Bupropion was found to be beneficial in adolescents with what comorbid conditions?
A
ADHD and MDD
3
Q
Bupropion ADEs
A
Less appetite suppression and weight loss (compared to stimulants)
4
Q
Bupropion in prepubertal children
A
Bupropion is metabolized faster in these patients, so BID dosing is needed
5
Q
TCAs used in ADHD
A
Imipramine, despiramine, nortriptyline
6
Q
How long does it take to see an effect from TCAs?
A
Up to 4 weeks
7
Q
TCAs ADEs
A
sedation/dizziness, constipation, heart block, weight gain, OD toxicity, rapid heart beat
