ActHIB, PedvaxHIB, Hiberix (Hib)

Question 1

TYPE:

Answer 1

Inactive

Question 2

ROUTE:

Answer 2

IM

Question 3

INDICATION:

Answer 3

Prevention of invasive disease caused by Haemophilus influenzae type b (Hib) in infants and children aged:

– ActHIB: 2 to 18 mo

– PedvaxHIB: 2 to 71 mo

– Hiberix: 15 mo to 4 yrs

Note: Hiberix is not approved for primary immunization

Question 4

DOSE:

Answer 4

0.5 mL

Question 5

OF DOSES:

Answer 5

3-4 doses

Question 6

FREQUENCY:

Answer 6

ActHib (primary & booster):
– Give 4 doses total, spaced at age 2 months, 4 months, 6 months, and 12–15 month (booster dose)

PedvaxHIB (primary & booster):
– Give 3 doses total, spaced at age 2 months, 4 months, 12–15 months (booster dose)

Hiberix (booster only):
– Give 1 dose total, at 15 months ‐ 4 years of age (booster dose)

Notes:

• • Dose #1 of Hib vaccine should not be given earlier than age 6 weeks
• • Give final dose (booster dose) no earlier than age 12 months and a minimum of 8 weeks after the previous dose
• • Hib vaccines are interchangeable; however, if different brands of Hib vaccines are administered for dose #1 and dose #2, a total of 3 doses is necessary to complete the primary series in infants.
• • Any Hib vaccine may be used for the booster dose.
• • Hib is not routinely given to children age 5 years and older.

Question 7

CONTRAINDICATIONS:

Answer 7

A) Previous anaphylaxis to this vaccine or to any of its components
B) Age younger than 6 weeks

Question 8

PRECAUTIONS:

Answer 8

Moderate or severe acute illness with or without fever

Question 9

ADVERSE REACTIONS:

Answer 9

Injection Site: pain, swelling, and erythema

Systemic: fever, drowsiness, and irritability