Acanthosis Nigricans Flashcards
1
Q
What are the causes?
A
T2DM
GI Malignancy
PCOS
Cushing syndrome
Acromegaly
Hypothyroidism
Prader Willi
Insulin resistance leads to increased insulin secretion causing proliferation of fibroblasts and keratinocytes
2
Q
What are clinical features?
A
Symmetrical dark brown/black velvety patches of skin
Present in axilla, groin or neck
3
Q
What is the management?
A
Identify and treat underlying cause
Consider topical keratolytics e.g. retinoids
Evaluate malignancy risk
