ABx coverage

Question 1

names, coverage, SE of 1 gen pen

Answer 1

• Pen G and V
• ## Gram + cocci, but aureus can resist

Question 2

names, coverage, SE of 2 gen pen

Answer 2

• Amox, ampicillin

- Gram + cocci and some gram - (h. inf., E. coli) and enterooccus

Question 3

names, coverage, SE of 3 gen pen

Answer 3

cloxacillin

- same as 1st gen, but excellent A. aureus

Question 4

names, coverage, SE of 4 gen pen

Answer 4

• Piperacillin

- same as 3rd plus pleudomonas

Question 5

names, coverage, SE of 1 gen cephs

Answer 5

• cephalexin and cefazolin

- exc. gram + cocci and some gram - bac

Question 6

names, coverage, SE of 2 gen cephs

Answer 6

• cefuroxime and cefotetan

- slightly better Gram - coverage - H. influ

Question 7

names, coverage, SE of 3 gen cephs

Answer 7

• ceftriaxone, ceftazidime
• excellent Gram -
• cefazadime covers psudomonas

Question 8

names, coverage, SE of carbapenems

Answer 8

meropenem, imipenem

- very broad spectrum

Question 9

names, coverage, SE of clindaymcin

Answer 9

• good for Gram + cocci and anaerobes

- strong assoc. with C diff

Question 10

names, coverage, SE of vanco

Answer 10

• good gram + and also MRSA

- can cause red man Syndrome

Question 11

names, coverage, SE of macrolides

Answer 11

• erethyromycine, azithro

- good gram +, poor gram -, good atyicals (legionella, mycoplama, chlam)

Question 12

names, coverage, SE of aminoglycoside

Answer 12

gentamycin, tobramycin

• aerobic gram -, can help with synergy in endocard.
• nephro and ototoxic

Question 13

names, coverage, SE of tetracyclines

Answer 13

doxycycline, tetracycline

• wide range of odds: borriela (lyme), ricketsia, mycoplasma, chlam
• can cause tooth discoloration

Question 14

names, coverage, SE of TMP-SMX

Answer 14

wide spectrum

- can cause hyperK and renal impairment

Question 15

names, coverage, SE of metronidozole

Answer 15

• exellent anaerobes

- good for C. diff.

Question 16

names, coverage, SE of flouroquinolones

Answer 16

Cipro
- gram - including pseudomonas
- limited gram pos
Levoflozxin or moxiflo - resps
- improved gram pos coverage