ABX: antivirales Flashcards

1
Q

MoA aciclovir y valaciclovir

A

inhibir la DNA polimerasa viral

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2
Q

EA aciclovir

A

Raros: rash, cefalea, hematuria, neurotoxicidad

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3
Q

EA ganciclovir y valganciclovir

A

neutropenia y trombocitopenia
SNC: cefalea, confusión, psicosis, convulsiones, coma

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4
Q

indicaciones ganciclovir y valganciclovir

A
  • neumonía, retinitis y colitis por CMV
  • queratoconjuntivitis herpética
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5
Q

MoA oseltamivir y zanamivir

A

inhibidor de la neuraminidasa

influenza

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6
Q

MoA Amantadina y rimantadina

A

inhibe el canal protónico M2 vírico

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7
Q

fármacos para el tratamiento de la hepatitis B

A

tenofovir
lamivudina

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8
Q

MoA tenofovir y Lamivudina

A

inhb transcriptasa inversa

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9
Q

EA tenofovir

A

> 10% astenia, diarrea, náusea
Casos raros de acidosis

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10
Q

EA lamivudina

A

Hepatitis fatal
acidosis

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11
Q

IFNa2A
IFNa2B

A

interfiere con viral replication

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12
Q

Rivabirina MoA

A

inhb formación de ARN mensajero

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13
Q

EA rivabirina

A
  • hemólisis, mielosupresión
  • VR: apnea, neumotórax, paro cardiaco
  • Teratogénico y embriotóxica, médicos embarazadas NO nebulizaciones
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