Abdominal: Gastro-oesophageal Reflux Disease Flashcards

1
Q

What is GORD?

A

Gastro-oesophageal reflux disease

  • Chronic relapsing condition
  • Stomach contents rises into oesophagus
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2
Q

What can cause GORD?

A
  • hiatal hernia
  • impaired oesophageal clearance
  • delayed gastric emptying
  • impaired mucosal defensive factors
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3
Q

What risk factors are associated with GORD?

A
  • stress/anxiety
  • drugs (Anti-inflammatories e.g. ibuprofen)
  • fat, chocolate, coffee
  • alcohol
  • large meals
  • smoking
  • hiatus hernia
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4
Q

What advice would you give to a patient if they have GORD?

A
  • eat smaller/more frequent meals
  • raise head end of bed
  • lose weight if over weight
  • find ways to relax
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5
Q

What would you advise against if a patient has GORD?

A
  • avoid food/drink that triggers symptoms
  • don’t eat before bed
  • don’t wear clothes tight around chest
  • don’t smoke
  • don’t drink too much alcohol
  • don’t stop taking prescribed medicine without talking to a doctor first
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6
Q

How does GORD present?

A
  • heartburn
  • regurgitation of food/acid
  • patient complains of pain when drinking hot liquids or alcohol
  • bad breath
  • hoarse throat
  • bloating/belching/hiccuping
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7
Q

what is dyspepsia?

A

a group of symptoms that alert doctors to consider disease of the upper GI tract including:

  • upper abdominal pain or discomfort, heartburn, gastric reflux, nausea, or vomiting.
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8
Q

what conditions present in a similar way to GORD?

A
  • Hiatus hernia

- Cardiac Ischaemic pain

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9
Q

what investigations do you use to diagnose GORD?

A

Diagnosis can be made without investigation.

If needed:

  • endoscopy
  • intraluminal monitoring (pH of oesophagus)
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10
Q

when should you refer a patient with suspected GORD for an endoscopy?

A

If GORD presented with GI bleeding.

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11
Q

what intervention should be made for uninvestigated dyspepsia?

A
  • 2 week of PPI

- test for H pylori

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12
Q

What over the counter medication can be used for GORD?

A

Alginate-containing antacids (10 mL three times daily)

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13
Q

what do antacids do?

A
  • over-the-counter medication for GORD

- form a gel or ‘foam raft’ with gastric contents to reduce reflux

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14
Q

side effects of antacids?

A

Magnesium-containing antacids tend to cause diarrhoea.

Aluminium-containing compounds may cause constipation.

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15
Q

If antacids fail to treat GORD what else can be purchased over the counter?

A

H2-receptor antagonists

(e.g. cimetidine, ranitidine, famotidine and nizatidine) are frequently used for acid suppression

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16
Q

What medication would you prescribe to treat GORD?

A

Proton pump inhibitors (PPIs)

omeprazole, rabeprazole, lansoprazole, pantoprazole, esomeprazole

17
Q

What do Proton pump inhibitors (PPIs) do?

A

inhibit gastric hydrogen/potassium-ATPase

PPIs reduce gastric acid secretion by up to 90%

18
Q

What intervention should be made for GORD?

A
  1. manage investigated ‘reflux like’ symptoms as uninvestigated dyspepsia
  2. offer PPI
  3. discuss how patient can manage their own symptoms
19
Q

What surgery can be offered for GORD?

A

Laparoscopic Fundoplication

20
Q

When should you consider a Laparoscopic Fundoplication for a GORD patient?

A
  • confirmed diagnosis, adequate symptom control but do not wish to continue medication long term
  • confirmed diagnosis, adequate symptom control but cannot tolerate acid suppression therapy
21
Q

what complications can arise due to GORD?

A

peptic stricture
Barrett’s Oesophagus
Ulcers

22
Q

What other healthcare professionals might be involved in a GORD patients care?

A
  • nutritionist: control new diet/weightloss
  • alcohol support group
  • smoking cessation group