Aani Micro: Pregnancy + Vaccines

Question 1

Which organism causes slapped cheek ?

Answer 1

Parvovirus B19 (5th disease)

Question 2

Another name for slapped cheek?

Answer 2

5th disease

Erythema Infectiosum

Question 3

Symptoms of parvovirus B19?

Answer 3

Red rash on cheeks

Transient aplastic crisis (cos it destroys erythroblasts and megakaryocytes)

Question 4

tx of parvovirus?

Answer 4

Intrauterine transfusions if < 20 weeks pregnant

Question 5

Which family of viruses does rubella belong to?

Answer 5

Togaviridae

Question 6

What are the symptoms of congenital rubella syndrome (CRS)?

Answer 6

EYES BRAIN HEART
Before 10 weeks: really bad!
Cataracts, glaucoma, hearing loss, mental retardation, heart disease (PDA), meningioencephalitis

If between 13 and 18 weeks - milder - hearing loss/retinopathy

Can lead to miscarriage or stillbirth esp before 8 weeks

Question 7

How is rubella transmitted?

Answer 7

Respiratory

Question 8

Symptoms of non-congenital rubella

Answer 8

Low grade fever
Macular-papular rash (exanthem) on the face-
spreads to the trunk and limbs and usually fades after three days (often referred to as three-day measles)

Question 9

What is a common cause of sensorineural hearing loss in kids?

Answer 9

Infection with CMV

Question 10

Which conditions are associated with blueberry muffin rash?

Answer 10

Rubella
CMV
Metastatic neuroblastoma

Question 11

Treatment of CMV in kids?

Answer 11

Ganciclovir IV

Valganciclovir PO