Aani Micro: Fever, Malaria etc Flashcards
What temp etc would be considered pyrexia of unknown origin?
> 38.3 degrees
persisting for 3 weeks with no diagnosis despite treatment for 1 week
What do you do if a pt has febrile neutropenia?
MED EMERGENCY:
Take 2 culture samples then treat with Abx asap
Look for conditions that need neutrophils e.g. fungal/bacterial
If pt has PUO and is HIV positive- what are you thinking for the differentials?
TB
Kaposi’s sarcoma
PCP
CMV
What causes typhoid?
Samonella Typhi and Paratyphi
What are the key symptoms of typhoid?
Fever, abdo pain, diarrhoea Headache Hepatomegaly ROSE SPOTS on abdo (in 30%) relative bradycardia constipation
What is the gram stain of typhoid?
Gram neg bacilli
Management of Typhoid?
Notifiable
Supportive (IV fluids)
Oral.IV Abx:
IV Ceftriaxone, cipro(fluroquinalone) - reduced susceptability
Examples of spotted fevers?
Rikettsia
Rocky Mountain
How do you pass on Rikettsia?
Zoonoses Via Tics/mites
Tx of spotted fevers?
IV Doxycycline
What are the different species that cause Malaria?
Plasmodium Falciparium
Plasmodium Vivax
Plasmodium Ovale
Plasmodium Malariae
In which organism’s infection would you found Schnuffner’s dots?
Plasmodium Ovale and Plasmodium Vivax
Describe the cell findings in P. Falciparum?
Ring forms (trophozoites) in RBCs and Banana/cresent gametocytes
How do you treat the differnt types of Malaria?
Falciparum:
- atovaquone+proguanil (malatone)
- artemisin
- quinine+doxy/clinda
Vivax and Oval: Chloraquine then Primaquine
When can you not have Primaquine?
Pregnancy