A&P Part 3 Flashcards

1
Q

responsible for carrying o2 and food to all the cells & CO2 and wastes from the cells, fluid and electrolytes for the maintenance of homeostasis, transports hormones and enzymes, transports antibodies to guard againsts infections, and controls body temperature

A

cardiovascular system

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2
Q

normal blood volume

A

4.73L

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3
Q

the process through which a cell undergoes changes in gene expression to become a more specific type of cell

A

Cellular differentiation or simply cell differentiation

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4
Q

gives rise to a class of leukocytes known as lymphocytes which include the various T cells, B cells, and natural killer cells, all of which function in immunity

A

Lymphoid stem cells

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5
Q

gives rise to all the other formed elements, including erythrocytes; megakaryocytes that produce platelets; and a myeloblast lineage that gives rise to monocytes and three forms of granular leukocytes

A

Myeloid stem cells

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6
Q

a glycoprotein hormone

prompts the production of erythrocytes

A

Erythroproietin

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7
Q

a glycoprotein hormone produced by the liver and kidneys

triggers in the development of megakaryocytes into platelets

A

Thrombopoietin

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8
Q

glycoproteins secreted by a wide variety of cells, including bone marrow, leukocytes, macrophages, fibroblasts and endothelial cells

A

Cytokines

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9
Q

are cells that have granules in the cytoplasm

A

granulocytes

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10
Q

cells that do not have granules in the cytoplasm (lymphocytes and monocytes)

A

Non-granulocytes

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11
Q

commonly known as red blood cell

primary function is to pick up inhaled oxygen from the lungs and transport it to the body’s tissues and to pick up some (about 24%) carbon dioxide waste at the tissues and transport it to the lungs for exhalation

A

Erythrocyte

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12
Q

what is an immature erythrocyte called

A

reticulocyte

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13
Q

increased retic count means that a lot of RBC’s are being _____, a decreased retic count means that RBC production is ______

A

produced; slower

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14
Q

are biconcave disks

provides a greater surface area across which gas exchanges can occur, relative to its volume

A

Erythrocyte

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15
Q

Large molecule made up of proteins and iron

A

Hemoglobin

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16
Q

Causes the body to assume a yellowish tings associated with jaundice

A

Bilirubin

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17
Q

Caused by a lack of intrinsic factor in the digestive tract

A

Pernicious anemia

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18
Q

Is required for the absorption of Vit B12, which is necessary for normal maturing of RBC’s

A

Intrinsic factor

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19
Q

Failure of bone marrow to produce enough RBCs as well as WBCs and platelets

A

Aplastic Anemia

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20
Q

Caused by an excessive destruction of RBC’s often because they ate deformed

treatment is splenectomy

A

Hemolytic Anemia

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21
Q

An inherited condition typically occurring in individuals from the Middle East, the Mediterranean, African and Southeast Asia, in which maturation of the RBCs does not proceed normally

Treatment is blood transfusions

A

Thalassemia

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22
Q

an elevated RBC count

blood disorder that causes your body to produce too many red blood cells

treatment is phlebotomy on a regular basis, every 2-3 weeks

A

Polycythemia

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23
Q

commonly known as white blood cells

major component of the body’s defenses against diseases

protects the body against invading microorganisms and body cells with mutated DNA, and they clean up debris

A

Leukocyte

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24
Q

Leukocytosis

A

an increase in wbc

indicates an infection or virus

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25
Leukopenia
decrease in wbc that may indicate a virus or leukemia or chemotherapy
26
are rapid responders to the site of infection and are efficient phagocytes with a preference for bacteria captures and destroys the invading bacteria or microorganisms by setting traps and ingesting them
neutrophils
27
are often involved in conditions that are associated with excessive inflammation, such as allergies, asthma, and autoimmune diseases
eosinophils
28
the least common leukocytes releases two enzymes, histamine and heparin during allergic reactions
Basophils
29
granules of basophils release histamine which contributes to ____ and heparin to opposes to ____ _____
inflammation; blood clotting
30
are the second most common type of leukocyte has no granules in the cytoplasm
lymphocytes
31
can destroy potential threats without prior exposure to a particular pathogen
Natural Killer Cells (NKC)
32
plays a prominent role in defending the body against specific pathogen
B cell (B lymphocytes) and T cells (T lymphocytes)
33
produces antibodies that destroy antigens or the pathogen associated with a particular antigen
B cells
34
are key fighters in what's known as adaptive immune systems. fights only one type of intruder
T cells
35
originate from myeloid stem cells eats up waste in blood
Monocytes
36
referred to as thrombocytes not a cell but rather a fragment of the cytoplasm of a cell called megakaryocyte
platelets
37
when the wall of a vessel is damaged
Vasoconstriction
38
platelets begin to clump together, becomes spiked and sticky, and bind to the exposed collagen and endothelial lining. they simultaneously release chemicals from their granules into the plasma that further contribute to hemostasis
formation of primary platelet plug
39
normally is triggered by trauma PT is the test used to evaluate this pathway
The extrinsic pathway
40
begins in the bloodstream and is triggered by internal damage to the wall of the vessel PTT is the test used to evaluate this pathway
Intrinsic pathway
41
3 stages of clotting in the common pathway
1. tissue thromboplastin + blood Ca + several blood proteins = active tissue thromboplastin 2. prothrombin + thromboplastin + several blood proteins + Ca = thrombin 3. fibrinogen in the presence of thrombin produces fibrin (blood clot)
42
gradual degratdaion of the clot
fibrinolysis
43
medications to prevent clotting
coumadin, heparin, warfarin, aspirin
44
immune to malaria
duffy
45
A antigen and anti B antibody
type A
46
B antigen and anti A antibody
type B
47
both A and B antigen and no antibody
type AB
48
no antigen and both anti A and B antibodies
type O
49
the heart pumps nearly how many gallons of blood each day?
4000
50
pumps blood in sufficient amounts to meet the needs of the cells of the body for the substances that it transports
heart
51
avg heart contraction?
75 contractions per minute
52
located within the thoracic cavity, medially between the lungs in the space known as the mediastinum
the heart
53
the receiving chambers
right atrium and left atrium
54
contracts to push blood
right and left ventricle
55
tricuspid valve and mitral valve (bicuspid) guards the opening between the atria and ventricle allows blood to flow from the atria to the ventricles prevents the blood from back flowing from the ventricular into the atria
cuspid valve
56
pulmonary valve and aortic valve prevents the blood from flowing back into the ventricles from the pulmonary and aortic arteries
semilunar valve
57
two major types of cardiac muscle cells
myocardial contractile cells and myocardial conducting cells
58
constitutes the bulk of the cells in the atria and ventricles conducts impulses and are responsible for contractions that pump blood through the body
myocardial contractile cells
59
forms the conduction system of the heart
myocardial conducting cells
60
forms the bulk of the heart
myocardium
61
functions to supply the heart with blood
coronary arteries
62
___ ____ is where the oxygenated blood leaves the heart and start its journey through the body
left ventricle
63
the first of many branches off the aorta
coronary artery branches
64
supplies blood to the right atrium and right ventricle (where deoxygenated blood goes before heading to the lungs)
Right coronary Artery
65
supplies blood to the left atrium and left ventricle. this is where the oxygenated blood arrives from the lungs before the heart pumps it out to the rest of your body
left main coronary artery
66
normal cardiac rhythm is established by the ____ ____ has the highest inherent rate of depolarization and is known as the pacemaker of the heart
sinoatrial (SA) node
67
second clump of specialized myocardial conductive cells located in the inferior portion of the right atrium within the atrioventricular septum
atrioventricular (AV) node
68
a branch of fibers (nerve cells) that extends from your AV node. receives the electrical signal from the AV node and carries it to the Purkinje fibers
The bundle of HIS
69
branches of specialized nerve cells sends electrical signals very quickly to your right and left heart ventricles
Purkinje fibers
70
buildup of fatty material called plaque on the inside of the coronary arteries
arteriosclerosis
71
also known as heart attack blood clot plugs one of the branches of a coronary artery as it does frequently in coronary thrombosis or embolism
Myocardial infarction
72
Angina Myocardial Infarction Congestive Heart Failure Bacterial endocarditis Coronary heart disease
Diseases of the heart
73
delivers oxygen to vital organs and tissues and remove waste products includes veins, arteries, and capillaries
blood vessels
74
inner layer regulates blood pressure, prevents blood clots and keeps toxins out of your blood keeps your blood flowing smoothly
tunica intima
75
middle layer contains elastic fibers that keep your blood flowing in one direction helps vessels expand and contract
tunica media
76
outer layer contains nerves and tiny vessels delivers oxygen and nutrients from your blood to your cells and helps removes waste also gives vessels structure and support
Tunica Adventitia
77
leads away from the heart carry oxygenated blood to the body carry unoxygenated blood to the lungs
Arteries
78
small arteries
arterioles
79
the only artery that does not carry oxygen rich blood
pulmonary artery
80
carries blood towards the heart carries deoxygenated blood from the body to the heart carries oxygenated blood from the lungs to the heart
veins
81
small veins
venules
82
smallest blood vessels that connect the arterioles to the venules where gases, nutrients, waste product and other substances are exchanged
capillaries
83
one way drainage system that flows only toward the heart system of vessels, cells and organs that carries excess fluids to the bloodstream and filters pathogens from the blood
Lymphatic system
84
the complex collection of cells and organs that destroys or neutralizes pathogens that would otherwise cause disease or death
immune system
85
organs of the lymphatic system
bone marrow thymus lymph node Spleen Lymph
86
has the vital job of making white blood cells, red blood cells and platelets
bone marrow
87
most active during puberty where T-cells fully mature
thymus
88
bean-shaped glands that monitor and cleanse lymph as it filters through them clears out damaged cells and cancer cells also store lymphocytes and other immune system cells that attack and destroy harmful substances like bacteria
lymph node
89
Largest lymphatic organ Filters blood and removes cells that are old or not working properly Also keeps red blood cells and platelets available
Spleen
90
Tubes that form a complex network throughout your body
Lymphatic vessel
91
Two collecting ducts
Right lymphatic duct and thoracic duct
92
A collection of barriers, cells and soluble proteins that interact and communicate with each other in extraordinarily complex ways
Immune system
93
Three temporal phases
Barrier defences Innate immune responses Adaptive immune response
94
Skin and mucous membranes, which act instantaneously to prevent pathogenic invasion of the body tissue
Barrier defence
95
Rapid but nonspecific Consists of a variety of specialized cells and soluble factors
Innate immune response
96
Slower but specific and effective adaptive immune response Involves many cell types and soluble factors but is primarily controlled by white blood cells
Adaptive immune response
97
Function primarily by producing antibodies
B cells
98
Is any of the group of proteins that binds specifically to pathogen-associated molecules known as antigens
Antibody
99
A chemical structure on the surface of a pathogen that binds to T or B lymphocyte antigen receptors
Antigen
100
Does not secrete antibodies but performs a variety if functions in the adaptive immune response
T cells
101
a B cell that has differentiated in response to antigen binding, and has thereby gained the ability to secrete soluble antibodies
Plasma cell
102
A circulating blood cell that contains cytotoxic (cell-killing) granules in its extensive cytoplasm Among the body’s first lines of defence against viruses and certain types of cancer
Natural Killer cells
103
Releases antibodies in response to antigens Are also called plasmacytes or effector cells
Plasma cells
104
Remembers antigens
Memory cells