92. Abnormal serum calcium Flashcards
what hormones regualte calcium
PTH
Vitamin D
calcitonin
net effect PTH on calcium and phosphate
increases calcium
decreases phosphate
net effect vitamin D on calcium and phosphate
increases calcium
increases phosphate
net effect calcitonin on calcium and phosphate
decreases calcium
decreases phosphate
what truggers the release of PTH
low levels of calcium
how does PTH influence vitamin d levels
PTH stimulates kidneys to convert to active vitamin D –> calcium and phosphate absorption
causes hypocalcaemia
low PTH
- hypoparathyrpid
- hypomagnesia
- overtreatment of hyperthyroid (cincalet)
low vitamin D
increased deposition in bones
- bisphosphonates
CKD (inability to convert to active vit D, calcium bind to retained phosphate)
Pseudohypoparathyroid
Rhabdomyolysis/tumour lysis (ca binds to released phosphate)