26. Red eye Flashcards

1
Q

history taking red eye

A

Sudden onset? Photophobia? Pain? Blurred vision? Pupil size?

Contact lens wearer? Until we know what is going on I would strongly advise you to not wear contact lenses. Do you have glasses you can wear?

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2
Q

red flags red eye

A

Decreased visual acuity = acute angle closure glaucoma, anterior uveitis

Photophobia = keratitis

Significant pain

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3
Q

examiantion red eye

A

CN 2,3,4,6 esp visual acuity with snellen chart, pupils and RAPD, pain on movement?

BP, BP, temperature, regional lymph nodes, look for signs of systemic disease/illness

to complete:
- fluorescin
- intraocualr pressure
- opthalmoscopy

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4
Q

serious causes of red eye that you need to rule out

A

Acute glaucoma
Anterior uveitis
Corneal causes
Corneal ulcer and contact lens-related red eye
Corneal foreign body

Neonatal conjunctivitis
Trauma
Penetrating eye injury
Chemical injuries, particularly alkali solutions
Scleritis
Endophthalmitis

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5
Q

glaucomacute angle closure claucoma presentation

A

PC: unilateral pain in the eye, red eye, headache, blurring of vision with lights seen surrounded by halos, nausea and vomiting, occurs in evening

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6
Q

what in medical history/drug history should you ask about ?acute angle closure glacuoma

A

MHx: recent pupil dilation using phenylephrine

DHx: tricyclics (antimuscarinics)

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7
Q

o/e red eye

A

o/e: reduced visual acuity, tender hard eye, fixed and mid-dilated pupil which is unresponsive to bright light

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8
Q

plan ?acute angle closure glaucoma in priamry care

A
  1. Admit immediately for specialist ophthalmology assessment
  • If immediate admission is not possible, start emergency treatment in primary care:
  1. Let the person lie flat with their face up and head not supported by pillows, as this may relieve some of the pressure on the angle.
    + If the drugs are available, give: pilocarpine eye drops, one drop of 2% in blue eyes or 4% in brown eyes; acetazolamide 500 mg orally to reduce production of aqueous humour (provided that there are no contraindications); analgesia; and an anti-emetic, if required.
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9
Q

investigations acute angle closure

A

tonometry to assess for elevated IOP

gonioscopy (literally looking, oscopy, at the angle, gonio): a special lens for the slit lamp that allows visualisation of the angle

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10
Q

plan ?acute angle closure glacuoma in secondary care - initial and defincitive

A

initial
1. IV/oral actetazolomide
+ parasympatheicomimetic eg topical pilocarpine
+ beta blockers eg timolol
+ alpha-2 antagonist eg apraclonidine

defintive
1. Laser peripheral iridotomy

= creates a tiny hole in the peripheral iris → aqueous humour flowing to the angle

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11
Q

drug class actezolomide? how does it work

A

Acetazolamide is a carbonic anhydrase inhibitor which works by reducing the secretion of aqueous humor

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12
Q

how do beta vlockers work for acute angle closure glaucoma

A

reduce intraocular pressure by decreasing the rate of production of aqueous humor

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13
Q

why does pilocarpine work in acute angle closure glacuoma

A

Pilocarpine is a topical miotic - pulls iris away from trabecular meshwork to allow improved drainage of aqueous humor

(parasympatheticomimetic)

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14
Q

causes of acute angle closure glaucoma

A

Age-related changes in the structure of trabecular meshwork
Pupil dilating drops, such as phenylephrine
Systemic antimuscarinic medicines, such as tricyclics, can precipitate acute glaucoma

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15
Q

presentation anterior uveitis. histroy and exam

A

PC: acute onset pain, blurred vision and photophobia

o/e: small, fixed oval pupil, ciliary flush

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16
Q

visible fluid level in the eye

A

associated with anterior uveitis and keratitis

hypopyon; describes pus and inflammatory cells in the anterior chamber, often resulting in a visible fluid level

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17
Q

conditions associated with anterior uveitis

A

ankylosing spondylitis
reactive arthritis
ulcerative colitis, Crohn’s disease
Behcet’s disease
sarcoidosis: bilateral disease may be seen

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18
Q

management anterior uveitis

A

urgent review by ophthalmology
cycloplegics (dilates the pupil which helps to relieve pain and photophobia) e.g. Atropine, cyclopentolate
steroid eye drops

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19
Q

what is keratitis

A

inflammation of the cornea

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20
Q

causes of keratitis

A

viral = hsv

bacterial
- staph aureus
- pseudomonas aergionosa in contact lens wearers

fungal
amoebic
parasitic

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21
Q

features keratitis

A

red eye: pain and erythema
photophobia
foreign body, gritty sensation
hypopyon may be seen
Normal visual acuity unless ulceration

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22
Q

management of infectious keratitis

A

refer contact lens wearer for same day assessment

topical antibiotics
typically quinolones are used first-line
cycloplegic for pain relief
e.g. cyclopentolate

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23
Q

complications of keratitis

A

corneal scarring/corneal ulcer
perforation
endophthalmitis
visual loss

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24
Q

risk factors for corneal ulcer

A

contact lens use

vitamin A deficiency: a particular problem in the developing world

recent infectious keratitis

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25
features that are seen particualrly in corneal ulcer
eye pain photophobia watering of the eye
26
management of ?corneal ulcer
focal fluorescein staining of the cornea can show corneal ulceration with corneal haze Refer urgently to ophthalmologist to consider infective, autoimmune causes dn for definitive care
27
presentation corneal foreign body
PC: Sudden onset discomfort/FB sensation, watering eye May occur whilst hammering or chiselling without eye protection or following minor trauma to the eye. A contact lens may have been ‘lost’ and cause FB sensation
28
invetsigation corneal foreign body
Fluorescein with blue light may show corneal ulceration/abrasion
29
management foreign body in eye
Refer to opthalmology urgently, make nil by mouth, tetanus, CT scan - Anaesthetise eye with topical local anaesthetic (proxymetacaine, tetracaine or oxybuprocaine) to allow examination and treatment - Gently pick up foreign body with cotton bud/irrigate lavishly with sterile saline. Recheck for FB. the bevel of a needle may also be used. - Protect eye with an eye shield until local anaesthetic has worn off and give topical chloramphenicol for 3 days. - If unable to remove FB or evidence of corneal abrasion, speak to senior or on-call opthalmologist
30
presentation conjunctivitis. How do the different causes present differently
PC: red eye, irritation/grittiness, discharge (watery, mucoid, sticky or purulent), morning stickiness, transient blurring of vision related to discharge Bacterial: purulent discharge, Eyes may be 'stuck together' in the morning. One then both eyes Viral: clear discharge, Recent URTI, Preauricular lymph nodes. One then both eyes Allergic: prominent itch, eyelids swollen, history of atopy
31
in conjunctivitis what should not be present
should be no significant pain, should be no photophobia, should be normal visual acuity
32
plan infective conjunctivitis? what do you need to check about the patient
normally a self-limiting condition that usually settles without treatment within 1-2 weeks if purulent - swab to rule out gonococcal infection 1. Chloramphenicol drops or ointment 0. Topical fusidic acid is an alternative and should be used for pregnant women. contact lens users: topical fluoresceins should be used to identify any corneal staining treatment as above contact lens should not be worn during an episode of conjunctivitis
33
how is chloramphenicol given in conjunctivitis
Chloramphenicol drops are given 2-3 hourly (while awake) initially for 2 days then 6 hourly for a week. Chloramphenicol ointment is given qds initially
34
infection control advice conjunctivitis
advice should be given not to share towels school exclusion is not necessary
35
management allergic conjunctivitis
first-line: topical or systemic antihistamines second-line: topical mast-cell stabilisers, e.g. Sodium cromoglicate and nedocromil
36
what is the difference in presentation scleritis vs episcleritis? how can you confirm this by invetsigation?
scleritis is classically painful wheras episcleritis is not in episcleritis, the injected vessels are mobile when gentle pressure is applied on the sclera phenylephrine drops may be used to differentiate between episcleritis and scleritis phenylephrine blanches the conjunctival and episcleral vessels but not the scleral vessels if the eye redness improves after phenylephrine a diagnosis of episcleritis can be made
37
cause of episcleritis
The majority of cases are idiopathic, associated conditions include: - inflammatory bowel disease - rheumatoid arthritis
38
causes of episcleritis
The majority of cases are idiopathic, associated conditions include: inflammatory bowel disease rheumatoid arthritis
39
features episcleritis
- red eye - classically not painful (in comparison to scleritis) - watering and mild photophobia may be present
40
management of episcleritis
conservative artificial tears may sometimes be used
41
risk factors for scleirits
rheumatoid arthritis: the most commonly associated condition systemic lupus erythematosus sarcoidosis granulomatosis with polyangiitis
42
features scleritis
red eye classically painful (in comparison to episcleritis), but sometimes only mild pain/discomfort is present watering and photophobia are common gradual decrease in vision
43
management scleritis
same-day assessment by an ophthalmologist oral NSAIDs are typically used first-line oral glucocorticoids may be used for more severe presentations immunosuppressive drugs for resistant cases (and also to treat any underlying associated diseases)
44
presentation subconjunctival ahemorrhage
PC: diffuse area of bright red blood under the conjunctiva May have FB sensation, no other symptoms (no photophobia, no pain, no altered vision)
45
manageemnt subconjunctival ahemorrhage
Check BP for malignant haemorrhage If recurrent check FBC and clotting, may need eye protection eg tape at night if swollen and unable to close Speak to ophthalmologist only if recurrent or severe
46
what is blepharitis
Blepharitis is inflammation of the eyelid margins. It may due to either meibomian gland dysfunction (common, posterior blepharitis) or seborrhoeic dermatitis/staphylococcal infection (less common, anterior blepharitis).
47
pathophysiology blepharitis
meibomian gland dysfunction (common, posterior blepharitis) The meibomian glands secrete oil on to the eye surface to prevent rapid evaporation of the tear film. Any problem affecting the meibomian glands (as in blepharitis) can hence cause drying of the eyes which in turns leads to irritation
48
presentation blepharitis
symptoms are usually bilateral grittiness and discomfort, particularly around the eyelid margins eyes may be sticky in the morning eyelid margins may be red. Swollen eyelids may be seen in staphylococcal blepharitis styes and chalazions are more common in patients with blepharitis secondary conjunctivitis may occur
49
management if blepharitis
- hot compress 2x per day - 'lid hygeine' mechanical removal of the debris from lid margins using cotton wool buds, boiled water and baby shampoo - artificial tears may be given for symptom relief
50
what is a stye? managment?
infection in sebacous glands/sweat glands management: hot compresses and analgesia Topical antibiotics (e.g., chloramphenicol) may be considered if it is associated with conjunctivitis or if symptoms are persistent.
51
what is a chalazion?
A chalazion occurs when a Meibomian gland becomes blocked and swells. It is often called a Meibomian cyst. It presents with a swelling in the eyelid that is typically not tender (however, it can be tender and red). Treatment is with warm compresses and gentle massage towards the eyelashes (to encourage drainage). Rarely, surgical drainage may be required.
52
what is keratoconjunctivitis sicca
dry eyes chronic bilateral desiccaion of the conjunctiva and cornea due to inadequate tear film
53
what is sjogrens syndrome
an autoimmune disorder affecting exocrine glands resulting in dry mucosal surfaces. It may be primary (PSS) or secondary to rheumatoid arthritis or other connective tissue disorders, where it usually develops around 10 years after the initial onset. Sjogren's syndrome is much more common in females (ratio 9:1).
54
features sjogrens
dry eyes: keratoconjunctivitis sicca dry mouth vaginal dryness arthralgia Raynaud's, myalgia sensory polyneuropathy recurrent episodes of parotitis renal tubular acidosis (usually subclinical)
55
autoantibodies sjogrens
rheumatoid factor (RF) positive in nearly 50% of patients ANA positive in 70% anti-Ro (SSA) antibodies in 70% of patients with PSS anti-La (SSB) antibodies in 30% of patients with PSS
56
what test can be used sjogrens
Schirmer's test: filter paper near conjunctival sac to measure tear formation
57
management sjogrens
Artificial tears (e.g., polyvinyl alcohol eye drops during the day and carbomer gel at night) Artificial saliva Vaginal lubricants Pilocarpine (oral) can be used to stimulate tear and saliva production Hydroxychloroquine may be considered, mainly in patients with associated joint pain
58
complications exocrine wise - sjogrens
Eye problems, such as keratoconjunctivitis sicca and corneal ulcers Oral problems, such as dental cavities and candida infections Vaginal problems, such as candida infection and sexual dysfunction
59
complications sjogrens
Pneumonia Bronchiectasis Non-Hodgkins lymphoma Peripheral neuropathy Vasculitis Renal impairment
60
61
Pre-septal/perioribital vs orbital cellulitis
Preseptal cellulitis is sometimes also referred to as periorbital cellulitis. It is an infection of the soft tissues anterior to the orbital septum - this includes the eyelids, skin and subcutaneous tissue of the face, but not the contents of the orbit. This is in contrast to orbital cellulitis, which is an infection of the soft tissues behind the orbital septum, and is a much more serious infection. Orbital signs (pain on movement of the eye, restriction of eye movements, proptosis, visual disturbance, chemosis, RAPD) must be absent in preseptal cellulitis - their presence would indicate orbital cellulitis
62
epidemiology preseptal celulitis and orbital cellulitis
- Preseptal cellulitis occurs most commonly in children - 80% of patients are under 10 and the median age of presentation is 21 months - It is more common in the winter due to the increased prevalence of respiratory tract infections. orbital cellulitis - Mean age of hospitalisation 7-12 years
63
Management of preseptal and of orbital cellulitis
1. Refer to secondary care, orbital is much more time critical 1. CT with contrast to differentiate between + FBC, blood culture, swab of any discharge Periorbital: often oral co-amoxiclav and observation Orbital: IV abx
64
what often precedes periorbital/orbital cellulitis
sinus infection, facial infection, insect bite
65
most common causative organisms preseptal/orbital cellulitis
Staph. aureus, Staph. epidermidis, streptococci and anaerobic bacteria
66
Approach to eye trauma
History - detail of injury (specifics) Exam - vision - fluirescin dye, slit lamp ?puncture ?foreign body ?laceration Plan - refer to opthalmology urgent on-call - NBM - CT - eye shield
67
when to swab conjunctivitis
purulent discharge - suspect gonococcal/STI