8.7 Mood Disorders

Question 1

• bad mood: sad, depressed, anxious, apprehensive, guilty

- may be associated with depression and anxiety disorders

Answer 1

dysphoric mood

Question 2

• moderately variable mood, appropriate to circumstances

- no/little pathology

Answer 2

euthymic mood

Question 3

• elation, irritability, hilarity

- may be associated with manic phase (bipolar)

Answer 3

euphoric mood

Question 4

change in behavioral and psychological functioning that results in impairment in social, occupational and personal functioning characterized by persisten sad or irritable mood, loss of interest, change in appetite, difficulty sleeping, psychomotor agitation, loss of energy…..

Answer 4

depression

Question 5

5 or more symptoms of depression met, and 2 week duration

-can have post partum onset, or seasonal onset

Answer 5

major depressive disorder

Question 6

2 or more symptoms met and 2 year duration, more chronic in course but less severe

Answer 6

persistent depressive disorder

Question 7

suicide attempts in men are _________ frequent than women but attempts are more __________

Answer 7

less, violent and successful

Question 8

rates of suicide peak at age _________ for African Americans and Native Americans, then fall

Answer 8

25-35

Question 9

hypersecretion of ________ from the hypothalamus linked to depression, as well as atrophy of the __________

Answer 9

cortisol, hippocampus

Question 10

bipolar mood disorders are diagnosed by the presence of _________ episodes

Answer 10

manic and hypomanic

Question 11

• distinct period of abnormally and persistently elevated, expansive, and irritable mood last one week
• 3 or more symptoms met: inflated self esteem, decreased need for sleep, more talkative, flights of ideas, distractibility, increased goal directed activity

Answer 11

bipolar I

Question 12

bipolar II mood disorder involves a distinct period of abnormally and persistently elevated, expansive, or irritable mood, lasting ____ days

Answer 12

4

Question 13

2 years of numerous hypomanic episodes and depressive episodes, duration of 1 year and children, and the person is not without the symptoms for more than 2 years at a time

Answer 13

cyclothymic disorder

Question 14

in bipolar patients, hyperintensities seen in _________ networks

Answer 14

fronto-temporal

Question 15

in bipolar patients, neuronal _________ alterations in cell membranes

Answer 15

phospholipid

Question 16

-mania: elevation of ________ and _________, deficiency in depression

Answer 16

norepinephrine and glutamate

Question 17

rapid assessment of depression assesses what 2 aspects?

Answer 17

depressed mood and anhedonia

Question 18

most effective overall thymoleptic (mood altering medication)?

Answer 18

lithium

Question 19

slow dose initiation due to risk of stevens-johnson syndrome, reduces suicide risk in bipolar patients?

Answer 19

lamotrigine