8.6 Diagnostic Medicine

Question 1

the estimated likelihood of a specific diagnosis prior to application of a diagnostic test; based on clinical features, prevalence, setting, experience and judgement

Answer 1

pre-test probability

Question 2

typically measured by sensitivity and specificity

Answer 2

diagnostic accuracy

Question 3

if a test is useless the sensitivity and specificity will add to?

Answer 3

100%

Question 4

why can’t use the positive and negative predictive values from a study?

Answer 4

b/c the pretest probability of the disease in your patient is not the pretest probability of the disease in the study

Question 5

clinical importance of a test is determined by both the _________ of disease and ____________

Answer 5

pretest probability, test accuracy

Question 6

the most clinically useful measure of diagnostic test accuracy, indicates how much a given test result will lower the pretest probability of the target disorder

Answer 6

likelihood ratio