8-Mutations and genetic disease Flashcards
1
Q
List the different types of DNA mutations
A
Point mutations Insertions and deletions Gene deletions Translocations Complex chromosomal rearrangements
2
Q
What are transitions?
A
Interchanges of two-rng purines or of one-ring pyrimidines- involve bases of similar change
3
Q
What are transversions?
A
Interchanges of purine for pyrimidine bases
4
Q
What are more commons transitions or transversions?
A
Transitions
5
Q
What does UTR mean?
A
Untranscribed region
6
Q
What is the effect of a mutation in the coding sequence?
A
Change the protein or stop translation
7
Q
What is the effect of a mutation in the promoter or non-coding regions
A
Alters expression levels
