6..polymovirda Flashcards
What type of genome does Polyomaviridae have?
Double-stranded circular DNA (dsDNA).
What is the structure of Polyomaviridae?
Non-enveloped, icosahedral capsid.
Which hosts are infected by Polyomaviridae?
Humans and monkeys.
What diseases can human Polyomaviruses cause?
Neurological diseases, renal diseases, and potentially human cancers.
What is the general distribution of human Polyomaviruses?
Wide distribution.
What disease is caused by BK virus?
Hemorrhagic cystitis, especially in bone marrow transplant patients.
How is BK virus diagnosed?
Detected in urine samples.
What disease is caused by JC virus?
Progressive multifocal leukoencephalopathy (PML), commonly seen in AIDS patients.
How is JC virus diagnosed?
Detected via CSF analysis and biopsy.
What is SV40 (Simian Virus 40)?
A monkey virus that can infect humans when it contaminated polio vaccines.
What is the human disease association of SV40?
Not associated with any known human diseases.
What are the characteristics of SV40?
Shows latency and persistence in infected cells.
