17.HHV7_Flashcards

Question 1

What is HHV-7 (Human Herpesvirus 7)?

Answer 1

HHV-7 is a T-lymphotropic virus primarily targeting T cells. It is immunologically distinct from HHV-6, with 50% DNA homology to HHV-6, and is classified as an orphan virus (no definitive disease association).

Question 2

How was HHV-7 first identified?

Answer 2

HHV-7 was first isolated from the blood of AIDS patients and healthy individuals (T cells).

Question 3

Who is primarily affected by HHV-7, and how is it transmitted?

Answer 3

HHV-7 mostly infects children during childhood. It is transmitted through saliva and establishes a persistent infection in the salivary glands.

Question 4

What percentage of healthy individuals carry HHV-7?

Answer 4

HHV-7 is found in 75% of healthy individuals.

Question 5

What disease is HHV-7 most commonly associated with?

Answer 5

HHV-7 is associated with Roseola Infantum (6th disease), similar to HHV-6B.

Question 6

What other conditions are associated with HHV-7?

Answer 6

1. Acute febrile respiratory disease.
2. Drug hypersensitivity reactions.
3. Epilepsy.
4. Pityriasis rosea (a skin rash condition).

Question 7

What role does HHV-7 play in relation to HHV-4 (EBV)?

Answer 7

HHV-7 may activate HHV-4 (EBV), causing a mononucleosis-like illness.

Question 8

Is there a reliable serological test for diagnosing HHV-7?

Answer 8

No, there is no reliable serological test for diagnosing HHV-7.

Question 9

What treatment is available for HHV-7?

Answer 9

No specific treatment is available for HHV-7.