2.Parvoviridae_Flashcards

1
Q

What type of genome does Parvoviridae have?

A

Linear single-stranded DNA (ssDNA) with negative sense DNA.

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2
Q

Describe the structure of Parvoviridae.

A

Small, rugged, icosahedral, and naked (non-enveloped).

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3
Q

What is the smallest DNA virus?

A

Parvoviridae.

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4
Q

Why is Parvoviridae heavily dependent on the host cell?

A

It has the smallest genome, making it reliant on host cell machinery for replication.

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5
Q

How is Parvoviridae commonly transmitted?

A

Fecal-oral route or respiratory droplets.

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6
Q

What types of organisms can Parvoviridae infect?

A

Vertebrates (humans and animals) and invertebrates.

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7
Q

What is Dependovirus, and how does it replicate?

A

Dependovirus (e.g., Adeno-associated virus, AAV) replicates only in the presence of a helper virus (e.g., adenovirus).

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8
Q

What makes Parvoviridae environmentally resilient?

A

Members of this family are highly resistant to inactivation.

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