6.3.3 - B cells

Question 1

Where are B cells made and matured?

Answer 1

Bone marrow

Question 2

Where are B cells concentrated?

Answer 2

Lymph glands

Question 3

What are opsonin antibodies?

Answer 3

antibodies that bind with antigens to act as markers so that phagocytes can recognise foreign cells and destroy them.

Question 4

What are agglutinin antibodies?

Answer 4

Antibodies that bind to antigens, causing foreign substances to clump together which prevents them from entering cells and reproducing.

Question 5

What are lysin antibodies?

Answer 5

Antibodies that bind to antigens and cause a foreign cells to rupture or disintegrate

Question 6

What are the 3 regions on a B cell from top to bottom?
(Antigen binding site downwards)

Answer 6

Variable regions
Constant regions
Transmembrane region

Question 7

What must B cells do before they release their antibodies in large quantities?

Answer 7

Become activated

Question 8

Describe the process of independent B cell activation.

Answer 8

A B cell and its membrane bound antibodies recognise and attach to antigens.
The B cell becomes activated, divides by mitosis and produces antibodies.

Question 9

Describe the process of T cell dependent activation.

Answer 9

A B cell antibody receptor matches with its complementary antigen. The B cell presents the antigen on its surface.
An activated T cell binds to the B cell, via this presented antigen.
The T cell produces cytokines which activate the B cell

Question 10

What happens after B cells become activated?

Answer 10

They divide by mitosis to form B memory cells and B effector cells

Question 11

What happens to B effector cells when they are produced from activated B cells?

Answer 11

They specialise to produce plasma cells