6/7/2023 Flashcards
Lotensin
Benazepril
Benazepril MOA
Prevents angiotensin I from being converted to angiotensin II by competitive inhibition, therefore preventing vasoconstriction.
Benazepril class
ACE inhibitor
Cogentin
Benztropine
Benztropine MOA
Anticholinergic and antihistaminic effects
Benztropine class
Anti-Parkinson agent, anticholinergic
Avastin
Bevacizumab
Bevacizumab MOA
Inhibits VEGF signaling pathways, therefore preventing vascular proliferation
Bevacizumab class
Antineoplastic, VEGF inhibitor
Lumigan
Bimatoprost
Bimatoprost MOA
Synthetic analog of prostaglandin; decreases intraocular pressure by increasing outflow of aqueous humor.
Bimatoprost class
Prostaglandin
Velcade
Bortezomib
Bortezomib MOA
Reversibly inhibits chymotrypsin-like activity at the 26S proteasome, leading to activation of signaling cascades, cell cycle arrest, and apoptosis.
Bortezomib class
Antineoplastic, proteasome inhibitor
Lumify
Brimonidine
Brimonidine MOA
Alpha-2 adrenergic agonist; causes reduction of aqueous humor formation and increased uveoscleral outflow
Brimonidine class
Alpha-2 adrenergic agonist
Suboxone
Buprenorphine/Naloxone
Buprenorphine/Naloxone MOA
Buprenorphine - exerts analgesic effect via high affinity binding receptors in the CNS; partial mu agonist and weak kappa antagonist
Naloxone - opioid antagonist that competes with and displaces opioids at opioid receptor sites
Buprenorphine/Naloxone class
Opioid analgesic/opioid partial agonist
Zyban
Bupropion
Wellbutrin
Bupropion
Bupropion MOA
Inhibits neuronal uptake of norepinephrine and dopamine
Bupropion class
Dopamine/norepinephrine reuptake inhibitor, antidepressant
Buspirone MOA
high affinity for serotonin receptors; moderate affinity for dopamine D2 receptors
Buspirone class
Miscellaneous antianxiety agent
Jevtana
Cabazitaxel
Cabazitaxel MOA
Microtubule inhibitor; binds to tubulin, promoting assembly into microtubules and inhibiting their disassembly and stopping the cell cycle
Cabazitaxel class
Antimicrotubular antineoplastic agent; taxane derivative
Caffeine MOA
Increases levels of 3’5’ cAMP by inhibiting phosphodiesterase. CNS stimulant, which increases medullary respiratory center sensitivity to carbon dioxide, stimulates central inspiratory drive, and improves skeletal muscle contraction
Caffeine class
CNS stimulant; phosphodiesterase inhibitor
Cannabidiol MOA
unknonwn
Cannabidiol class
Cannabinoid; antiseizure agent
Capsaicin MOA
Agonist for transient receptor potential vanilloid 1 receptor (TRPV1), an ion channel receptor complex expressed on nociceptive nerve fibers in the skin. Causes initial stimulation of TRPV1-expressing cutaneous nociceptors that may cause painful sensations, followed by pain relief caused by downregulation of TRPV1-expressing nociceptive nerve endings.
Capsaicin class
Topical analgesic; TRPV1 agonist
Tegretol
Carbamazepine
Carbamazepine MOA
Decreases temporal stimulation leading to neural discharge by limiting influx of sodium ions across the cell membrane
Carbamazepine class
Antizeisure agent
Sinemet
Carbidopa/levodopa
Carbidopa/levodopa MOA
Carbidopa/levodopa class
Anti-parkinson agent
Rytary
Carbidopa/levodopa
Duopa
Carbidopa/levodopa
Carbidopa/levodopa MOA
Levodopa crosses the BBB where it is converted to dopamine
Carbidopa inhibits peripheral breakdown of levodopa by inhibiting its decarboxylation, thereby increasing available levodopa at the BBB