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Top 300 Drugs > 6/7/2023 > Flashcards

6/7/2023 Flashcards

1
Q

Lotensin

A

Benazepril

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2
Q

Benazepril MOA

A

Prevents angiotensin I from being converted to angiotensin II by competitive inhibition, therefore preventing vasoconstriction.

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3
Q

Benazepril class

A

ACE inhibitor

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4
Q

Cogentin

A

Benztropine

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5
Q

Benztropine MOA

A

Anticholinergic and antihistaminic effects

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6
Q

Benztropine class

A

Anti-Parkinson agent, anticholinergic

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7
Q

Avastin

A

Bevacizumab

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8
Q

Bevacizumab MOA

A

Inhibits VEGF signaling pathways, therefore preventing vascular proliferation

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9
Q

Bevacizumab class

A

Antineoplastic, VEGF inhibitor

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10
Q

Lumigan

A

Bimatoprost

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11
Q

Bimatoprost MOA

A

Synthetic analog of prostaglandin; decreases intraocular pressure by increasing outflow of aqueous humor.

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12
Q

Bimatoprost class

A

Prostaglandin

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13
Q

Velcade

A

Bortezomib

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14
Q

Bortezomib MOA

A

Reversibly inhibits chymotrypsin-like activity at the 26S proteasome, leading to activation of signaling cascades, cell cycle arrest, and apoptosis.

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15
Q

Bortezomib class

A

Antineoplastic, proteasome inhibitor

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16
Q

Lumify

A

Brimonidine

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17
Q

Brimonidine MOA

A

Alpha-2 adrenergic agonist; causes reduction of aqueous humor formation and increased uveoscleral outflow

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18
Q

Brimonidine class

A

Alpha-2 adrenergic agonist

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19
Q

Suboxone

A

Buprenorphine/Naloxone

20
Q

Buprenorphine/Naloxone MOA

A

Buprenorphine - exerts analgesic effect via high affinity binding receptors in the CNS; partial mu agonist and weak kappa antagonist

Naloxone - opioid antagonist that competes with and displaces opioids at opioid receptor sites

21
Q

Buprenorphine/Naloxone class

A

Opioid analgesic/opioid partial agonist

22
Q

Zyban

A

Bupropion

23
Q

Wellbutrin

A

Bupropion

24
Q

Bupropion MOA

A

Inhibits neuronal uptake of norepinephrine and dopamine

25
Q

Bupropion class

A

Dopamine/norepinephrine reuptake inhibitor, antidepressant

26
Q

Buspirone MOA

A

high affinity for serotonin receptors; moderate affinity for dopamine D2 receptors

27
Q

Buspirone class

A

Miscellaneous antianxiety agent

28
Q

Jevtana

A

Cabazitaxel

29
Q

Cabazitaxel MOA

A

Microtubule inhibitor; binds to tubulin, promoting assembly into microtubules and inhibiting their disassembly and stopping the cell cycle

30
Q

Cabazitaxel class

A

Antimicrotubular antineoplastic agent; taxane derivative

31
Q

Caffeine MOA

A

Increases levels of 3’5’ cAMP by inhibiting phosphodiesterase. CNS stimulant, which increases medullary respiratory center sensitivity to carbon dioxide, stimulates central inspiratory drive, and improves skeletal muscle contraction

32
Q

Caffeine class

A

CNS stimulant; phosphodiesterase inhibitor

33
Q

Cannabidiol MOA

A

unknonwn

34
Q

Cannabidiol class

A

Cannabinoid; antiseizure agent

35
Q

Capsaicin MOA

A

Agonist for transient receptor potential vanilloid 1 receptor (TRPV1), an ion channel receptor complex expressed on nociceptive nerve fibers in the skin. Causes initial stimulation of TRPV1-expressing cutaneous nociceptors that may cause painful sensations, followed by pain relief caused by downregulation of TRPV1-expressing nociceptive nerve endings.

36
Q

Capsaicin class

A

Topical analgesic; TRPV1 agonist

37
Q

Tegretol

A

Carbamazepine

38
Q

Carbamazepine MOA

A

Decreases temporal stimulation leading to neural discharge by limiting influx of sodium ions across the cell membrane

39
Q

Carbamazepine class

A

Antizeisure agent

40
Q

Sinemet

A

Carbidopa/levodopa

41
Q

Carbidopa/levodopa MOA

A
42
Q

Carbidopa/levodopa class

A

Anti-parkinson agent

43
Q

Rytary

A

Carbidopa/levodopa

44
Q

Duopa

A

Carbidopa/levodopa

45
Q

Carbidopa/levodopa MOA

A

Levodopa crosses the BBB where it is converted to dopamine

Carbidopa inhibits peripheral breakdown of levodopa by inhibiting its decarboxylation, thereby increasing available levodopa at the BBB

Top 300 Drugs (9 decks)

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