6/6/2023 Flashcards

1
Q

Orencia

A

Abatacept

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2
Q

Abatacept MOA

A

Co-stimulator blocker; blocks early activation of T cells

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3
Q

Abatacept class

A

non-TNF biologic DMARD

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4
Q

Acetaminophen MOA

A

Blocks the action of COX3 in the brain, resulting in decreased prostaglandin synthesis

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5
Q

Acetaminophen class

A

Analgesic

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6
Q

Zovirax

A

Acyclovir

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7
Q

Acyclovir MOA

A

inhibits DNA synthesis and viral replication by competing with deoxyguanosine triphosphate for viral DNA polymerase and being incorporated into viral DNA

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8
Q

Acyclovir class

A

antiviral agent

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9
Q

Humira

A

Adalimumab

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10
Q

Amjevita

A

Adalimumab

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11
Q

Adalimumab MOA

A

bind to TNF-a to neutralize its biological activity

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12
Q

Adalimumab class

A

biologic DMARD, TNF

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13
Q

Differin

A

Adapalene

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14
Q

Adapalene MOA

A

Retinoid-like compound; modulates cellular differentiation, keratinization, and inflammatory processes

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15
Q

Adapalene class

A

Retinoic acid derivative

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16
Q

Campath

A

Alemtuzumab

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17
Q

Alemtuzumab MOA

A

Targets cell surface glycoprotein CD52

18
Q

Alemtuzumab class

A

antineoplastic agent, anti-CD52

19
Q

Zyloprim

A

Allopurinol

20
Q

Allopurinol MOA

A

Prevents synthesis of urate from hypoxanthine and xanthine

21
Q

Allopurinol class

A

Xanthine oxidase inhibitor

22
Q

Alprazolam MOA

A

Binds to benzodiazepine receptor on the postsynaptic GABA neuron within the CNS, enhancing the inhibitory effect of GABA and causing increased neuronal membrane permeability to chloride ions, which makes the neuron less excitable

23
Q

Alprazolam class

A

Benzodiazepine

24
Q

Elavil

A

Amitriptyline

25
Q

Amitriptyline MOA

A

Increases synaptic concentration of serotonin and/or norepinephrine in the CNS by inhibiting their reuptake

26
Q

Amitriptyline class

A

Tricyclic antidepressant

27
Q

Amoxicillin MOA

A

Inhibits bacterial wall synthesis by binding to one or more penicillin-binding proteins, which inhibits the final transpeptidation step of peptidoglycan synthesis in the bacterial cell wall. The incomplete cell wall biosynthesis eventually leads to lysis of the bacterial cell.

28
Q

Amoxicillin class

A

aminopenicillin

29
Q

Amoxicillin/clavulanate MOA

A

Amoxicillin disrupts bacterial cell wall synthesis by binding to one or more penicillin-binding proteins and preventing the final transpeptidation step of peptidoglycan synthesis in the bacterial cell wall.

Clavulanate is a beta lactamase inhibitor.

30
Q

Amoxicillin/Clavulanate class

A

Penicillin + beta lactamase inhibitor combination

31
Q

Amphotec

A

Amphotericin B

32
Q

Abelcet

A

Amphotericin B

33
Q

Amphotericin B MOA

A

Binds to ergosterol altering cell membrane permeability in susceptible fungi, causing leakage of cell components and subsequent cell death.

34
Q

Amphotericin class

A

Antifungal agent

35
Q

Arimidex

A

Anastrozole

36
Q

Anastrozole MOA

A

Inhibits aromatase, preventing the conversion of androstenedione to estrone, and testosterone to estradiol, thereby decreasing tumor mass or delaying progression in patients with tumors sensitive to hormones.

37
Q

Anastrozole class

A

Aromatase inhibitor

38
Q

Abilify

A

Aripiprazole

39
Q

Aripiprazole MOA

A

Antipsychotic with affinity for dopamine and serotonin receptors, alpha1 adrenergic receptors, and histamine receptors. Also acts as a serotonin reuptake inhibitor.

40
Q

Aripiprazole class

A

Second generation antipsychotic