6/6/2023 Flashcards
Orencia
Abatacept
Abatacept MOA
Co-stimulator blocker; blocks early activation of T cells
Abatacept class
non-TNF biologic DMARD
Acetaminophen MOA
Blocks the action of COX3 in the brain, resulting in decreased prostaglandin synthesis
Acetaminophen class
Analgesic
Zovirax
Acyclovir
Acyclovir MOA
inhibits DNA synthesis and viral replication by competing with deoxyguanosine triphosphate for viral DNA polymerase and being incorporated into viral DNA
Acyclovir class
antiviral agent
Humira
Adalimumab
Amjevita
Adalimumab
Adalimumab MOA
bind to TNF-a to neutralize its biological activity
Adalimumab class
biologic DMARD, TNF
Differin
Adapalene
Adapalene MOA
Retinoid-like compound; modulates cellular differentiation, keratinization, and inflammatory processes
Adapalene class
Retinoic acid derivative
Campath
Alemtuzumab
Alemtuzumab MOA
Targets cell surface glycoprotein CD52
Alemtuzumab class
antineoplastic agent, anti-CD52
Zyloprim
Allopurinol
Allopurinol MOA
Prevents synthesis of urate from hypoxanthine and xanthine
Allopurinol class
Xanthine oxidase inhibitor
Alprazolam MOA
Binds to benzodiazepine receptor on the postsynaptic GABA neuron within the CNS, enhancing the inhibitory effect of GABA and causing increased neuronal membrane permeability to chloride ions, which makes the neuron less excitable
Alprazolam class
Benzodiazepine
Elavil
Amitriptyline
Amitriptyline MOA
Increases synaptic concentration of serotonin and/or norepinephrine in the CNS by inhibiting their reuptake
Amitriptyline class
Tricyclic antidepressant
Amoxicillin MOA
Inhibits bacterial wall synthesis by binding to one or more penicillin-binding proteins, which inhibits the final transpeptidation step of peptidoglycan synthesis in the bacterial cell wall. The incomplete cell wall biosynthesis eventually leads to lysis of the bacterial cell.
Amoxicillin class
aminopenicillin
Amoxicillin/clavulanate MOA
Amoxicillin disrupts bacterial cell wall synthesis by binding to one or more penicillin-binding proteins and preventing the final transpeptidation step of peptidoglycan synthesis in the bacterial cell wall.
Clavulanate is a beta lactamase inhibitor.
Amoxicillin/Clavulanate class
Penicillin + beta lactamase inhibitor combination
Amphotec
Amphotericin B
Abelcet
Amphotericin B
Amphotericin B MOA
Binds to ergosterol altering cell membrane permeability in susceptible fungi, causing leakage of cell components and subsequent cell death.
Amphotericin class
Antifungal agent
Arimidex
Anastrozole
Anastrozole MOA
Inhibits aromatase, preventing the conversion of androstenedione to estrone, and testosterone to estradiol, thereby decreasing tumor mass or delaying progression in patients with tumors sensitive to hormones.
Anastrozole class
Aromatase inhibitor
Abilify
Aripiprazole
Aripiprazole MOA
Antipsychotic with affinity for dopamine and serotonin receptors, alpha1 adrenergic receptors, and histamine receptors. Also acts as a serotonin reuptake inhibitor.
Aripiprazole class
Second generation antipsychotic