5.2 lab - bone formation and growth

Question 1

this bone cell type is a specialized macrophage

Answer 1

osteoclast

Question 2

T/F both periosteal and endosteal surfaces are completely lined with cells

Answer 2

true

Question 3

how is an osteoclast formed?

Answer 3

from fusion of multiple monocytes

Question 4

how to identify osteoclast?

Answer 4

large and multinucleated on surface of bone

-howship’s lacuna - thin rim of demineralized bone being resorbed by osteoclast

Question 5

howship’s lacuna

Answer 5

thin rim of demineralized bone being resorbed by osteoclast

Question 6

2 layers of periosteum

Answer 6

cellular (bone lining cells)
fibrous layer (condensed fibrous layer)

Question 7

how can you identify an osteoprogenitor cell?

Answer 7

can’t

will look like bone lining cell, can’t really tell difference

Question 8

thin rim of demineralized bone being deposited by osteoblast

Answer 8

osteoid

Question 9

thin rim of demineralized bone beneath an…

• osteoblast
• osteoclast

Answer 9

osteoid

howship’s lacuna

Question 10

T/F normal adult hyaline cartilage is avascular

Answer 10

true

blood supply brings calcium and triggers mineralization of cartilage matrix in endochondral ossification

Question 11

isogenous groups

Answer 11

clusters of chondrocytes

formed from parent chondrocyte and all hang around together

Question 12

what is the appearance of isogenous groups in the epiphyseal growth plate? why?

Answer 12

linear

because matrix is growing in one direction

Question 13

what is the difference between perichondrium and periosteum?

Answer 13

essentially the same, each has inner cellular and outer fibrous layers, just one surrounds cartilage and one surrounds bone