50. CANCER CELLS Flashcards
1
Q
- Do cancer cells exhibit Density-Dependent Inhibition or Anchorage Dependence?
A
- no
2
Q
- What leads to a clump of overlapping cancer cells forming?
A
- cancer cells continue to divide well beyond a single layer
3
Q
- What is Transformation?
A
- the process by which a normal cell becomes a cancer cell
4
Q
- What are three ways in which Cancer cells do not normally respond to the body’s control mechanisms?
A
- they make their own growth factors
- they have a signalling pathways always ON
- they have abnormal cell cycle control
5
Q
- What two kinds of tumours do Cancer Cells form?
A
- BENIGN TUMOURS:
- not invasive
- contained at a particular site
- MALIGNANT TUMOURS:
- invasive
- they can spread to other organs
6
Q
- What are Malignant Tumours?
A
- they invade surrounding tissues
- they export cells to other parts of the body
- they may form secondary tumours
- this is known as Metastasising
7
Q
- What are 6 characteristics of Cancer Cells?
A
- They resist Cell Death
- They sustain Proliferative Signalling
- They evade Growth Suppressors
- They activate invasion and metastasis
- They enable replicative immortality
- They induce angiogenesis
ANGIOGENESIS:
- the formation of new blood vessels
8
Q
- What causes Cancer Cells?
A
- cancer is caused by an accumulation of multiple
mutations - a heterogeneity of tumours
- diverse physiological pathways and tissue
specificity
9
Q
- What is Precision Oncology?
A
- this is the science of using a patient’s genetics to
create a treatment plan - this plan is targeted to the molecular
characteristics of their cancer
10
Q
- Read through Summary 1.
Does everything make sense?
A
- yes
11
Q
- Read through Summary 2.
Does everything make sense?
A
- yes
12
Q
- Read through Summary 3.
Does everything make sense?
A
- yes
13
Q
- Read through Summary 4.
Does everything make sense?
A
- yes
14
Q
- Read through Summary 5.
Does everything make sense?
A
- yes
15
Q
- Read through Summary 6.
Does everything make sense?
A
- yes