5/4 Flashcards

1
Q

Spinal chord compression workup

A

Surgery consult
Neuroimaging
IV steroid (maybe)

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2
Q

How long to treat a single episode of depression

A

6 months

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3
Q

Ethylene glycol tox

A

Hypocalcemia and calcium oxalate deposition in kidneys

–>Massive anion gap (HCO3

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4
Q

Ethylene glycol tx tx

A

Fomepizole or ethanol to inhibit alcohol dehydrogenase

can also give sodium bicarb to alleviate acidosis

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5
Q

Cat bite bacteria to worry about and tx

A

Pasturella

Tx w/ Amox/clavulanate

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6
Q

Growth and weight by 1 year old

A

Weight should triple

Height should increase by 50%

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7
Q

PSVT EKG and tx

A

Sudden onset, regular, and narrow complex tachycardia

Adenosine (slows AV nodal conduction)

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8
Q

1st step for A-fib w/ RVR

A

Rate control with B-blockers or CCB (Dilitazam)

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9
Q

Aromatase def features

A

XX- normal internal genitalia w/ ambiguous external genetalia, literal hypertrophy
High FSH/LH with low estrogen

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10
Q

McCune-Albright triad

A

Cafe au last spots
Polycystic fibrous dysplasia
Endocrine hyperfunction

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11
Q

Gold standard for dx’ing VUR

A

Voiding cystourethrogram

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12
Q

Tx for all children w/ a UTI age 2-24 monhs

A

Renal and bladder US to evaluate for any anomalies that may predispose to VUR

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13
Q

When are loop diuretics recommended for SIADH

A

If urine osmolarity is more than 2x serum osmolarity

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14
Q

If a girl has lots of early pubic hair but no breast budding, where is the premature adrenarche coming from

A

Adrenals

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15
Q

What causes isolated precocious puberty

A

Early HPA activation

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16
Q

What should be suspected in a well appearing neonate with painless bloody stools

A

Milk or soy protein proctoclitis

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17
Q

Tx for sphincter of oddi dysfunction

A

ERCP w/ sphincterotomy

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18
Q

2 big causes for pediatric myocarditis

A

Cox B

Adenovirus

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19
Q

Viral myocarditis featuers

A

Acute left heart failure signs after viral syndrome
Holsytolic murmur from functioning mitral regurg
Hepatomegaly and cardiomegaly

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20
Q

Biopsy shows endometrial hyperplasia: next step if atypia? if no atypia?

A

Atypia: Hysterectomy

No atypia: Progestin therapy

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21
Q

2 big burn sepsis bugs

A

S. aureus

Pseudomonas

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22
Q

Spherocytosis tests

A

Inc. MCHC
Osmotic fragility on acidified glycerol lysis test
Abnormal eosin-5-maleimide binding test

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23
Q

A reliable test gives what

A

Similar results on repeated measurements

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24
Q

Transferrin saturation highest in what

A

Thalassemia (Iron/TIBC)

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25
Antipsychotic most likely to increase prolactin
Risperidone
26
Aripiprazole MOA
Partial D2 agonist (rather than antagonist)
27
Epo side affects
1. Worsening of HTN 2. Headaches 3. Flu-like syndrome 4. Red cell aplasia
28
COPD exacerbation tx
1. Supplemental O2 (sat 88-92%) 2. Inhaled bronchodilators (b2 agonist and anticholinergics) 3. Antibiotics 4. Systemic glucocorticoids
29
Mild intermittent asthma
1. Symptoms
30
Acetaminophen OD guidlines
Charcoal if
31
What type of cancer increases Vit D production
All lymphomas
32
CML mutation? tx?
9:22 fusion of BCR/ABLE gene | Tx with imatinib (non-receptor tyrosine kinase inhibitor)
33
What is isolated systolic hypertension? tx?
HTN in elderly patients caused by decreased elasticity of the arterial wall Tx: thiazide, ACE, or CCB
34
Best drug to slow progression of DM nephropathy
Ace inhibitors
35
Meningococcal vaccination schedule
Age 11-12 (or 13-18 if not before) | Booster at 16-21 (if primary before 16th birthday)
36
1st step when gastric adenocarcinoma is diagnosed
Staging w/ CT scan
37
First line tx for PCOS
Weight loss and COC therapy
38
Surgical hx + bad ab pain + persistent variable decelerations worry about?
Uterine rupture | Do laparotomy and delivery (C-section)
39
Contra to catheter in trauma patient
Obvious pelvic injury or blood at the urethral meatus
40
Chronic tearing that is often unilateral in neonate
Dacryostenosis (nasolacrimal duct obstruction)
41
Endometriosis exam
May show rectovaginal tenderness or tenderness w/ movement of uterus due to tissue in rectovaginal septum, peritoneum, uterosacral ligaments
42
Thickening or uterosacral ligaments on exam
Think endometriosis
43
How does endometriosis incr. infertility risk
Chronic inflammation and adhesion formation
44
Edema in nephritic glomerulonephritis due to
Decreased GFR and retention of Na and H2O by kidneys
45
Breast feeding mastitis tx
Dicloxacillin or cephalexin
46
Things that can cause pulsus paradoxus besides tamponade? why?
Asthma and COPD (due to greatly exaggerated drop in intrathoracic pressure during inspiration)
47
Think what when CT shows gas in gallbladder? who gets it?
Emphysematous colitis | Seen in immunocompromised people (DM)
48
Aortic rupture CXR
Widened mediastinum and left sided hemothorax
49
Food borne vs non infantile botulism
Foodborn- ingestion of preformed C botulinum toxin | Non-foodborne- Ingestion of SPORES from the environment
50
Marfan mutation
Fibrillin-1
51
Visual acuity testing at well child visits
Infants: observe fixation and tracking Older infants: cover-uncover test Over 3: visual acuity testing begins
52
Who gets the rotavirus vaccine
2-8 months old (highest risk from severe dehydration at this age range)
53
Children who suffer from selective mutism features
Talkative at home but refuse to speak in specific settings, like school
54
Why gout in myeloproliferative disorders
Excessive turnover of purines and resulting increase in uric acid production
55
Why elevated BUN/Creatinine ratio in upper GI bleed
Increased urea production (from intestinal Hgb breakdown) and increased urea reabsorption (due to hypovolemia)
56
Why angina in aortic stenosis
Increased myocardial oxygen demand due to increased left ventricular mass
57
Hallmark of asbestosis imaging
Pleural plaques
58
Contact lens associated keratitis due to
Pseudomonas and Serratia
59
Eczema herpeticum features
Painful vesicular rash w/ "punched out" erosions and hemorrhagic crusting
60
MCC of death in acromegaly
Cardiovascular
61
Idiopathic (central) precocious puberty seen almost always in
Girls
62
Late onset CAH features
Advanced bone age Coarse axillary and pubic hair Severe cystic acne
63
Test to determine central vs peripheral precious puberty
LH level after GnRH stimulation (in gonadotropin independent (peripheral) LH will be low before and after)
64
Triad in disseminated gonococcal disease
1. Polyarthralgia 2. Tenosynovitis 3. Painless vesicopustular skin lesions
65
When should you suspect SBP
Any patient with cirrhosis and ascites accompanied by either fever or change in mental status
66
+ SBP test
Positive ascites fluid culture and neutrophil count >250mm3
67
When is confounding bias present
When at lest part of the exposure-disease relationship can be explained by another variable (confounder)
68
What is notorious for causing refractory hypokalemia
Hypomagnesemia (be sure to correct Mg and K)
69
Acute pancreatitis complicated by hypotension thought to arise from
Intravascular volume loss 2/2 local and systemic vascular endothelial injury
70
Smudge cells seen in
Chronic lymphocytic leukemia
71
What makes alcoholic hallucinations different from DT
24-48 hours of last drink and sensorium remains intact w/ stable vitals
72
GAD tx
SSRI or SNRI
73
What is increased in yolk sac tumor
AFP
74
What is increased in leydig cell tumors
Testosterone and Estrogen (Inc aromatase activity) w/ secondary inhibitio of LH and FSH
75
Most common ped's fracture
Supracondylar fracture of the humerus
76
Most common complication of the supracondylar fracture of the humerus
Entrapment of the brachial artery or median nerve
77
HELLP
Hemolysis Elevated Liver enzymes Low Platelets *Also RUQ pain*
78
What causes pulmonary edema in severe Preeclampsia
Increased systemic vascular resistance, capillary permeability, pulmonary cap hydrostatic pressure, and decreased albumin
79
Primary vaginal cancer characterized by
Bloody malodorous discharge and an irregular vaginal lesions | *dx by biopsy before excision*
80
Aspirin is a common trigger for bronchoconstriction in what asthma patients
Those with chronic rhinitis an nasal polyps
81
What is amantadine
Dopa agonist (PD)
82
Shape of Calcium oxalate crystals
Envelope
83
What is vaginismus caused by
Involuntary contraction of the perineal musculature (psychosocial underlying cause)
84
Two things that help ARDS (vent wise)
Low tidal volumes | PEEP
85
TB common cause of what dz
Primary adrenal insufficiency
86
All patients with precocious puberty and elevated LH should get what
Brain MRI with contrast
87
Primary tx for idiopathic GDPP? why?
RnRH agonist therapy to prevent premature epiphyseal plate fusion and maximize height potential
88
What grave's dz tx can temporarily make graves opthalmopathy worse
Radioactive iodine
89
What drug is contraindicated in acute MI w/ pulmonary edema
B-blockers (but good for MIs without)
90
Rubella vaccine in pregnancy
Not recommended but probably not harmful
91
Tx to reduce hypercalcemia in immobilized people
Hydration and bisphosphonates