49 - Sleep Flashcards
Body Temperature
Up in the day
Decreases when you fall asleep
Retino-hypothalamic Tract
Retina to the suprachiasmatic nucleus!!!!
Sleep Promoting NTs
Adenosine
Galanin
Wake Promoting NTs
Hypocretin/Orexin
Histamine
Melatonin
Circadian Rhythms
Close your eyes in bed
Alpha Activity
Stage 1
No alpha
Stage 2
K complex
12 - 14 cps activity (sleep spindle)
Stage 3
Deep sleep
Rhythmic
Stage REM
Low amplitude, mixed frequency
NO MUSCLE TONE
Variable heart and respiratory rate
REM Eye Movements
Deep sleep starts in the beginning of the night and tapers off.
REM sleep gets more frequent and longer.
Sleep Disrders
Insomnia
Hypersomnia
Parasomnia Disorders (sleepwalking, night terrors, bedwetting, grinding teeth, etc)
Parasomnias
Biological clock disorder!
Insomnia - Etiology
Medical Neurological Psychiatric or Psychological Environmental Situational
PRIMARY SLEEP DISORDER
Medications for Insomnia
Benzodiazepines Non-Benzodiazepines Melatonin agonists Low dose antidepressants - antihistaminic Orexin inhibitors