39 - NeuroScience - Vestibular & Occulomotor Systems Flashcards
2 Components of the vestibular system in the inner ear
Saccule & Utricle
Semicircular Canals
Saccule & Utricle
Linear Acceleration
Semicircular Canals
Angular Acceleration (3D) Activated by specific movements of the head with respect to the rest of the body.
Saccule, Utricle & Semicircular Canals
Activate peripheral projections of the vestibular ganglia
Hair Cells synapse on
Peripheral Dendrites of ganglion cells
Central projection of ganglion cells project to
Vestibular nuclei in Medulla & Pons (via CN VIII)
Afferents in CN VIII project to
Vestibular Nuclei
Cerebellum (Flocculus/Nodulus)
What makes the Trochlear Nerve so unique?!
Exits brainstem on dorsal surface
Crossed, Right CN IV controls Left Superior Oblique
Vestibular Nucleus
Complex
Collection of 4 nuclei:
Each is indistinguishable from a standard view of the brainstem, but connectivity is different.
Located in rostral medulla through middle-pons
Location of Occulomotor Nuclei
Midbrain (Occulomotor & Trochlear)
Pons (Abducens)
Vestibular System - 2 Descending Components
Lateral Vestibulospinal Tract (LVST)
Medial Vestibulospinal Tract (MVST)
Descending Vestibular System - Lateral Vestibulospinal Tract (ACTUALLY ONE OF THE MEDIAL DESCENDING SYSTEMS)
Emerges from projection neurons in Lateral Vestibular Nucleus (LVN)
Regulates activity of motor neurons to ipsilateral antigravity muscles
In spinal cord, its projections are in the Ventral Medial aspects of the white matter.
Descending Vestibular System - Medial Vestibulospinal Tract
Originates in Medial Vestibular Nucleus (MVN)
Only goes to cervical portion of the spinal cord
Stabliizes head position & coordinates head/eye movements
Vestibular System - 3 Ascending Components
Medial Longitudinal Fasciculus (MLF)
Projection to VPN of Thalamus
Projection to Cerebellum
Ascending Vestibular System - Medial Longitudinal Fasciculus (MLF)
Arises from Medial Superior & Inferior Nuclei
Coordinates eye movements via inputs to CN III, CN IV, CN VI