4.2 Skin Pathology III

Question 1

• caused by HPV
• keratotic papules
• 20% kids
• histo: thick granular layer, hyperkeratosis, papillary hyperplasia

Answer 1

verruca vulgaris (wart)

Question 2

-a keratinocyte with shrunken nucleus, halo around nucleus, hallmark of HPV

Answer 2

koilocyte

Question 3

• umbilicated papules
• direct transmission
• umbilication corresponds to widely dilated hair follicle openings, containing eosinophilic bodies (Viral particles) and a heavy lymphoid reaction

Answer 3

molluscum contagiosum

Question 4

• young adults, spring and fall
• trailing scale, christmas tree pattern
• herald plaque (original) then widespread eruption 2 weeks later
• mound of parakeratin on histo

Answer 4

pityriasis rosea

Question 5

• caused by staph aureus
• kids/young adults
• occurs on face/extremities
• honey colored crusts
• neutrophils and s. aureus colonies on histo

Answer 5

impetigo

Question 6

• dermatophytes
• direct contact transmission
• annular plaques

Answer 6

tinea (ringworm)

Question 7

• excoriated papules
• young, immunodeficient may have worse reactions
• eosinophils and sweat glands

Answer 7

insect bite reaction

Question 8

• direct transmission

- pruritic papules, itching worse at night

Answer 8

scabies

Question 9

• 4% of population, genetic/environmental
• beefy red plaques
• silver scale
• rete pegs elongated, thick epideermis, parakeratotic scales

Answer 9

psoriasis

Question 10

85% of young adults, papules and pustules, perifollicular inflammtion, open comedo

Answer 10

acne vulgaris

Question 11

-fair skinned adults, exaggerated blushing, facial telangiectasias, rhinophyma

Answer 11

rosacea

Question 12

wheals, transient and annular, due to mast cell degranulation, may get andioedema, on histo have dilated lymphatics and perivascular inflammation

Answer 12

urtricaria

Question 13

acute eruption,

Answer 13

erythema multiforme