40B - Lecture - Chapter #21 Flashcards
Tunica Interna
Inner portion next to blood
Contains:
Endothelium
Elastic Tissue
Tunica Media
Contains:
Smooth muscle
*Thinner in vein than artery
Tunica Externa
Contains:
Connective Tissue
*Thinner in vein than artery
Difference between leumen in artery and vein
Vein is wider / larger
Artery is smaller
Aneurysm
Weakening in blood vessel, usually arteries because they are under high blood pressure
Where does skeletal muscles help with blood flow?
In deep veins
Varicose Veins
Valve fails
Continuous Capillary
“Leaky”
Can exchange substances, small proteins
Contains: Pinocytic vesicle and intercellular cleft
Vascularizes: CNS, Muscle tissue, connective tissue, pulmonary capillaries
Fenestrated Capillary
“Leakier”
Contains: Fenestrated (pores) and intercellular cleft
Vascularizes: Kidney, Endocrine glands
Sinusoid Capillaries
“Leakiest”
Contains: Incomplete basement membrane, intercellular cleft (large gaps)
Vascularizes: RBM, Sleep, Liver
Filtration
Fluid out of capillaries
Reabsorption
Osmotic fluid into capillaries
What causes Filtration?
Blood pressure
Filters 20L/day
H2O + Solutes
What causes reabsorption?
Albumin = BCOP
Reabsorbs 17L/day, 3L/day goes to lymphatic capillaries
Net filtration
+ 10mm Hg
Net Reabsorption
-9 mm Hg
Edema
Excess fluid in interstitial area around tissues or cells
Causes of edema
Liver disease: Decrease in albumin
Kidney disease: Albumin is excreted
Pulmonary Edema
LEFT valve problem
Fluid backs up in lung
Peripheral Edema
RIGHT valve problem
Swelling in leg
Gets backed up inn IVC and SVC
Blood flow
Volume of blood and flows through any tissue in a given time period in ml/min
Mechanisms that effect blood flow
- BP
2. Vascular resistance: size of leumen, viscosity, total blood vessel length
Shock
Failure of the cardiovascular system to deliver enough oxygen and nutrients to meet the needs of cells
Hypovolemic Shock
Decrease blood volume, decrease blood pressure
