4- CAP Flashcards

1
Q

pneumonia can be characterised based on

A

site of acquisition

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2
Q

Nosocomial pneumonia includes

A

HAP and VAP

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3
Q

HCAP is no longer used but means

A

pneumonia in health care facilities (nursing homes, hemodialysis centers) or after recent hospitalisation

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4
Q

Risk factors for CAP

A
old age
chronic comorbidities (COPD)
viral respiratory tract infection
impaired airway protection
smoking, alcohol, opiod use
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5
Q

most frequent pathogens in CAP

A

streptococcus pneumoniae and respiratory viruses (note that in large cases, no pathogen is detected)

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6
Q

why is the incidence of pneumococcal pneumonia decreasing

A

due to pneumococcal vaccine rates

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7
Q

can you diagnose CAP without a chest x ray

A

no, there needs to be demonstration of infiltrate on chest imaging with associated symptoms

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8
Q

can x ray infiltrate pattern help differentiate etiology of pathogen

A

no

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9
Q

what is the next step if x ray is inconclusive

A

perform CT (often done in immunocompromised pts

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10
Q

most common scores used in CAP

A

pneumonia severity index (PSI/PORT score) and CURB-65

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11
Q

levels of severity of care in CAP

A
  • ambulatory care
  • hospital admission
  • intensive care unit
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12
Q

scores for ambulatory care in CAP

A

PSI 1-2

CURB-65 0 or 1 if old

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13
Q

when to have hospital admission in CAP

A

pts with O2 sat<92% on room air, PSI>3, and CURB-65 >1

signs of sepsis, rapidly progressing illness, inability to take oral medications, cognitive or functional impairement

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14
Q

who needs ICU admission for CAP

A

respiratory failure needing mechanical ventilation, sepsis needing vasopressor support 31

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15
Q

dx for CAP in ambulatory setting

A

microbiologic testing is not needed, empiric antibiotic therapy is successfull

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16
Q

dx for CAP in hospital admission setting

A

blood culture, sputum gram stain and culture, urinary antigen test for S. pneumonia and legionella, PCR on nasal swab, bronchoscopic specimens

17
Q

complications of CAP tx with no ID of organism first

A

clostridium difficile infection

18
Q

tx for ambulatory CAP

A
empiric tx (target S. pneumoniae, and atypical pathogens) - B lactam + macrolide (azithromycin, clarithromycin) or doxycyline
respiratory fluoroquinolone (levofloxacin)
19
Q

when to stop antibiotics for CAP

A

when pt has been afebrile for at least 48 hours

20
Q

what to remember when selecting an initial regimen for hospitalised pts with CAP

A

risk of infection with pseudomonas aeruginosa, or MRSA

21
Q

tx for inpatient CAP

A

empiric tx, and if risk of pseudomonas use IV piperacillin/tazobactan, carbapenem (anti pseudomonas B lactam and antipseudomonas fluoroquinolone)
for risk of MRSA use linezolid or glycopeptides

22
Q

3 pillars for prevention of CAP

A

smoking cessation
influenza vaccine for all pts
pneumococcal vaccine for at risk pts