20- Pulmonary tuberculosis Flashcards
when a person comes into contact with M tuberculosis what happens
95% of indv with an intact immune system control further replication of the bacilli, this ends in clearance or latent phase
results of TST and IGRA in case of LTBI
positive
what is used to dx active TB infection
- chest X ray Pet CT
- microscopy (sputum smears)
- culture based methods
- molecular tests
does active tb have fever
no
define tuberculoma
Which lobe is it most found in
is a well circumscribed nodule or a mass they occur in post/primary TB usually found in upper lobes 1-10 cm smooth and sharp margins
types of laryngeal TB
primary disease: direct invasion of bacilli into the larynx
secondary disease: via bronchiogenic spreadfrom advanced pulmonary TB or via hematogenous/lymphatic spread
tx of TB
isoniazid
RF for TB reactivation
HIV, organ transplant, silicosis, TNF alpha blockers, close contacts, kidney dialysis pts
Pulmonary complications of TB
hemoptysis, pneumothorax, bronchiectasis, extensive pulmonary destruction, malignancy, chronic pulmonary aspergillosis, NOT FEVER
Symptoms for reactivated TB
this is only symptomatic 2-3 years after beginning of reactivation; cough, weight loss, fever, night sweats, chest pain, dyspnea
Laryngeal TB appears on laryngoscopy as?
It can result in?
hyperemia, nodules, ulcerations, exophytic masses on true/false vocal chords, epiglottis
can lead to vocal chord paralysis
Sx for primary disease TB
NOT FEVER
- pleuritis chest pain with pleural effusion
- retrosternal and dull interscapular pain due to enlarged bronchial lymph nodes
RARE: fatigue, cough, arthralgia, pharyngitis
T/F routine hematology and biochemistry labs are normal in early pulmonary TB
T
Late dx: normocytic anemia, leukocytosis