38. Cancer chemotherapy V. (Small molecule signal transduction inhibitors)

Question 1

Which are the groups of small molecule signal transduction inhibitors?

Answer 1

• mTOR inhibitors
• Receptor tyrosine kinase
• Other kinase inhibitors
• Proteasome inhibitors
• Drugs influencing apoptosis
• Other types of inhibitors

Question 2

Which are the mTOR inhibitors?

Answer 2

• Everolimus
• Temsirolimus

Question 3

Which are the receptor tyrosine kinase inhibitors?

Answer 3

• Imatinib
• Erlotinib
• Ibrutinib
• Sunitinib, sorafenib
• Axitinib
• Regorafenib

Question 4

Which are the other kinase inhibitors?

Answer 4

• Vemurafenib
• Trametinib

Question 5

Which are the proteazome inhibitors?

Answer 5

• Bortezomib
• Carfilzomib
• Ixazomib

Question 6

Which are the drugs influencing apoptosis?

Answer 6

Venetoclax

Question 7

Which are the other types of inhibitors?

Answer 7

• Panobinostat
• Retinoids
  
  • Tretinoin
  • Alitretinoin
  • Bexaroten